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API | Excipient name:

Resmetirom 

Cas Number:

1432368-62-9 

Resmetirom is a type of Thyreomimetics

Thyreomimetics are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that mimic the actions of the thyroid hormones. These synthetic compounds are designed to interact with the thyroid hormone receptors and elicit similar effects as endogenous thyroid hormones, such as triiodothyronine (T3) and thyroxine (T4).

Thyroid hormones play a crucial role in regulating metabolism, growth, and development in the body. However, individuals with thyroid disorders, such as hypothyroidism or thyroid cancer, may have an impaired production of these hormones. Thyreomimetics offer a targeted therapeutic approach by acting as thyroid hormone agonists, stimulating the receptors and compensating for the deficiency.

These API subcategory drugs exhibit high selectivity and affinity for thyroid hormone receptors, ensuring minimal off-target effects. They are commonly used in the treatment of hypothyroidism, where the thyroid gland fails to produce adequate hormone levels. Thyreomimetics can help normalize metabolic processes and alleviate symptoms like fatigue, weight gain, and depression associated with hypothyroidism.

Furthermore, thyreomimetics are also employed in certain cases of thyroid cancer. By activating thyroid hormone receptors, they suppress the production of thyroid-stimulating hormone (TSH), which can promote tumor growth. This approach aids in the management of thyroid cancer by reducing TSH levels and inhibiting the proliferation of cancer cells.

In conclusion, thyreomimetics are a vital subcategory of pharmaceutical APIs used in the treatment of thyroid disorders. They act as synthetic thyroid hormone analogs, mimicking the effects of endogenous hormones and restoring normal physiological functions. With their targeted action and therapeutic benefits, thyreomimetics play a crucial role in improving the well-being of patients with thyroid-related conditions.

Resmetirom (Thyreomimetics), classified under Anti-Thyroid Agents

Anti-thyroid agents are a category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of thyroid disorders. These agents are specifically designed to target and inhibit the production or release of thyroid hormones in the body.

One commonly used anti-thyroid agent is propylthiouracil (PTU). PTU works by interfering with the synthesis of thyroid hormones within the thyroid gland, thereby reducing their production. Another widely used anti-thyroid agent is methimazole, which also acts by inhibiting thyroid hormone synthesis. These agents are typically prescribed for individuals with hyperthyroidism, a condition characterized by an overactive thyroid gland that produces an excessive amount of thyroid hormones.

Anti-thyroid agents are available in various forms, including tablets and solutions for oral administration. The dosage and duration of treatment may vary depending on the severity of the condition and individual patient factors.

It's important to note that anti-thyroid agents should be used under the guidance and supervision of a healthcare professional, as they may have potential side effects. These can include allergic reactions, liver toxicity, and blood disorders. Regular monitoring of thyroid function and liver function is typically recommended during treatment.

In summary, anti-thyroid agents are a class of pharmaceutical APIs used in the management of thyroid disorders. They work by inhibiting the production or release of thyroid hormones and are available in different formulations for oral administration. Proper medical guidance is essential for the safe and effective use of these agents.

• Shandong Chenghui Shuangda Pharmaceutical Co. Ltd. from China, product country of origin China
• Sichuan Elixir Pharmaceutical Co., Ltd from China, product country of origin China
• Apino Pharma Co., Ltd. from China, product country of origin China

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