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Looking for Adapalene 106685-40-9?

API | Excipient name:
Adapalene 
Synonyms:
Adaferin , Adapaleno , Adapalenum , Differine  
Cas Number:
106685-40-9 
DrugBank number:
DB00210 
Unique Ingredient Identifier:
1L4806J2QF

About Adapalene

You can find a short description about Adapalene here. Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris.

Adapalene has similar efficacy but a superior safety profile compared to tretinoin. Tazarotene is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women. Adapalene can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties6, and either adapalene alone, or adapalene BPO combination products, are commonly used to treat mild-to-severe acne. Differin®, produced by Galderma Labs, was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution. Differin was later made available as 0.1% gel, cream, or lotion, or 0.3% gel products. On December 8th, 2008, Galderma Labs gained FDA approval for Epiduo®, a 0.1% adapalene, 2.5% BPO combination gel.

More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.

Adapalene manufacturers | traders | suppliers

We have 8 companies offering Adapalene from 4 different countries.

Get in contact with the supplier of your choice:

  • Excella from Germany
  • Bal Pharma from India
  • Finorga from France
  • Shaoxing Hantai Pharma from China
  • Glenmark Pharma from India
  • Sun Pharma from India
  • Olon from Italy
  • Medichem from Spain

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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