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Ferulic acid | CAS No: 1135-24-6 | GMP-certified suppliers
A medication that offers potential antioxidant, anti-inflammatory, and cardiovascular support properties for research and development in diverse therapeutic areas.
Therapeutic categories
Product Snapshot
- Ferulic acid is an oral small molecule compound
- It is primarily investigated for antioxidant and anti-inflammatory applications
- The compound remains in experimental status without FDA or EMA approval
Clinical Overview
While ferulic acid is not currently approved for clinical use, it has been the subject of experimental research exploring a range of pharmacological activities. It is noted in the literature for potential anti-inflammatory, antioxidant, and cardiovascular effects. These properties are attributed to its chemical structure which enables free radical scavenging and modulation of oxidative stress pathways. However, specific mechanisms of action have not been fully elucidated and remain under investigation.
The compound's absorption, distribution, metabolism, and excretion (ADME) profile includes moderate bioavailability following oral administration, with metabolism involving conjugation processes such as glucuronidation and sulfation. It is typically cleared via renal excretion of metabolites. Detailed pharmacokinetic parameters are yet to be comprehensively characterized in clinical populations.
Safety and toxicity data for ferulic acid remain limited due to its experimental status. Preclinical studies indicate low acute toxicity, but comprehensive assessments including long-term toxicity, genotoxicity, or carcinogenicity have not been established. There is insufficient evidence to define contraindications or safety profiles in special populations.
Ferulic acid is used extensively in research settings and industrial applications, including as a laboratory reagent and component in formulations exploring antioxidative or anti-inflammatory potentials. It is not marketed under any approved pharmaceutical brand for therapeutic indications at this time.
From an API sourcing perspective, procurement should prioritize suppliers adhering to stringent quality standards, including appropriate characterization of purity, residual solvents, and absence of contaminants. Documentation supporting batch-to-batch consistency and compliance with pharmacopeial or regulatory guidelines is vital for research or development purposes.
Identification & chemistry
| Generic name | Ferulic acid |
|---|---|
| Molecule type | Small molecule |
| CAS | 1135-24-6 |
| UNII | AVM951ZWST |
| DrugBank ID | DB07767 |
Pharmacology
Targets
| Target | Organism | Actions |
|---|---|---|
| Endo-1,4-beta-xylanase Y | Clostridium thermocellum | |
| Endo-1,4-beta-xylanase Z | Clostridium thermocellum (strain ATCC 27405 / DSM 1237) | |
| Est1e | Butyrivibrio proteoclasticus |
Formulation & handling
- Ferulic acid is a small molecule typically formulated for oral administration due to its physicochemical properties.
- The moderate water solubility and logP suggest formulation strategies may require solubilization or use of appropriate excipients to enhance bioavailability.
- Caution is advised regarding potential interactions with herbs or supplements possessing anticoagulant or antiplatelet activity during formulation and patient counseling.
Regulatory status
Ferulic acid is a type of Analgesics
Analgesics are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that are commonly used to relieve pain. They are designed to alleviate discomfort by targeting the body's pain receptors or by reducing inflammation. Analgesics are widely utilized in the medical field to manage various types of pain, ranging from mild to severe.
One of the primary classes of analgesics is nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by inhibiting the production of prostaglandins, substances that contribute to pain and inflammation. This class includes well-known drugs like ibuprofen and naproxen. Another class of analgesics is opioids, which are derived from opium or synthetic compounds that mimic the effects of opium. Opioids act on the central nervous system to reduce pain perception and provide potent pain relief. Examples of opioids include morphine, codeine, and oxycodone.
Analgesics are available in various forms, such as tablets, capsules, creams, and injections, allowing for different routes of administration based on the patient's needs. They are commonly used to manage pain associated with conditions like arthritis, headaches, dental procedures, and post-operative recovery.
It is important to note that analgesics should be used under medical supervision, as improper use or overuse can lead to adverse effects, including gastrointestinal complications, addiction, and respiratory depression in the case of opioids. Therefore, it is crucial for healthcare professionals to assess each patient's individual needs and prescribe the appropriate analgesic and dosage.
In summary, analgesics are a vital category of pharmaceutical APIs used to alleviate pain by targeting pain receptors or reducing inflammation. With various classes and forms available, they provide valuable options for pain management when used responsibly and under medical guidance.
Ferulic acid API manufacturers & distributors
Compare qualified Ferulic acid API suppliers worldwide. We currently have 1 companies offering Ferulic acid API, with manufacturing taking place in 1 different countries. Use the table below to review supplier type, countries of origin, certifications, product portfolio and GMP audit availability.
| Supplier | Type | Country | Product origin | Certifications | Portfolio |
|---|---|---|---|---|---|
| Sinoway industrial Co.,Lt... | Distributor | China | China | CoA | 757 products |
When sending a request, specify which Ferulic acid API quality you need: for example EP (Ph. Eur.), USP, JP, BP, or another pharmacopoeial standard, as well as the required grade (base, salt, micronised, specific purity, etc.).
Use the list above to find high-quality Ferulic acid API suppliers. For example, you can select GMP, FDA or ISO certified suppliers. Visit our help page to learn more about sourcing APIs via Pharmaoffer.
