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Arylacenamide
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Looking for Arylacenamide API 132173-07-0?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Arylacenamide. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Arylacenamide
- Synonyms:
- Cas Number:
- 132173-07-0
- DrugBank number:
- DB05792
- Unique Ingredient Identifier:
- 9K6U3I1UR0
General Description:
Arylacenamide, identified by CAS number 132173-07-0, is a notable compound with significant therapeutic applications. Arylacenamide (SR31747) is a peripheral ligand that binds four proteins in human cells, i.e. SRBP-1, -2, HSI and its relative SRBP-2. It is a dual agent with both immunomodulatory and antiproliferative activities.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in cancer/tumors (unspecified), immunosuppressive, and prostate cancer. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Arylacenamide functions by: SR31747 blocks proliferation of human lymphocytes, modulates the expression of pro- and anti-inflammatory cytokines, and was shown to protect animals in vivo against acute and chronic inflammatory conditions such as acute graft-versus-host reaction, lethality induced by staphylococcal enterotoxin B and lipopolysaccharide or rheumatoid arthritis. Besides these immunomodulatory activities, the molecule also inhibits the proliferation of various tumor cell lines in vitro in a time- and concentration-dependent manner. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Arylacenamide belongs to the class of organic compounds known as styrenes. These are organic compounds containing an ethenylbenzene moiety, classified under the direct parent group Styrenes. This compound is a part of the Organic compounds, falling under the Benzenoids superclass, and categorized within the Benzene and substituted derivatives class, specifically within the Styrenes subclass.
Categories:
Arylacenamide is categorized under the following therapeutic classes: Cycloparaffins, Enzyme Inhibitors, Immunologic Factors, Receptors, sigma, antagonists & inhibitors. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Arylacenamide is a type of Anti-inflammatory Agents
Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.
Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.
Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.
In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.
