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Clobutinol hydrochloride API Manufacturers & Suppliers

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Looking for Clobutinol hydrochloride API 14860-49-2?

Description:
Here you will find a list of producers, manufacturers and distributors of Clobutinol hydrochloride. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Clobutinol hydrochloride 
Synonyms:
Clobutinol HCl  
Cas Number:
14860-49-2 
DrugBank number:
DB09004 
Unique Ingredient Identifier:
1NY2IX043A

About Clobutinol hydrochloride

Here you will find more information about Clobutinol hydrochloride. Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients.

Check who is selling Clobutinol hydrochloride in the overview above.

Clobutinol hydrochloride is a type of Antitussives


Antitussives are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of cough. These compounds act by suppressing or inhibiting the cough reflex, providing relief to individuals suffering from excessive or persistent coughing.

Antitussives work through various mechanisms to alleviate cough symptoms. One common approach involves targeting the central nervous system (CNS) to suppress the cough reflex. This can be achieved by modulating the activity of receptors, such as opioid receptors, in the brain. Opioid-based antitussives, such as codeine or hydrocodone, are often prescribed for cough suppression due to their effectiveness in dampening the cough reflex.

Another class of antitussives work by directly affecting the respiratory system. They typically act on the sensory nerves in the airways, reducing the sensitivity and irritability that triggers coughing. Examples of these antitussives include benzonatate and dextromethorphan. These compounds work locally in the respiratory tract to provide relief by numbing or soothing the irritated nerves.

Antitussives are available in various formulations, including tablets, capsules, syrups, and lozenges, catering to different patient needs. Their usage is widespread in both over-the-counter and prescription medications to alleviate cough symptoms caused by conditions such as the common cold, flu, allergies, or respiratory tract infections.

It is important to note that antitussives should be used as directed by healthcare professionals, as excessive or inappropriate use may lead to adverse effects or mask underlying conditions. Consulting a healthcare provider is recommended before starting any antitussive treatment, especially for individuals with pre-existing medical conditions or those taking other medications.

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