Aprotinin API Manufacturers
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Established in: 1980
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Employees: 30+
EU-GMP and DIN EN ISO 9001:2015
Pioneer in the fractionation of sheep plasma
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Looking for Aprotinin API 9087-70-1?
- Description:
- Here you will find a list of producers, manufacturers and traders of Aprotinin. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Aprotinin
- Synonyms:
- Cas Number:
- 9087-70-1
- DrugBank number:
- DB06692
- Unique Ingredient Identifier:
- 04XPW8C0FL
About Aprotinin
So, what does it do? Aprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). Since it demonstrates the capacity to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and liver surgery. For this use, it is typically administered by injection. The goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery.
Nevertheless, the drug was formally withdrawn worldwide in May of 2008 after studies confirmed that its use enhanced the risk of complications or death. The substance is consequently made available only for very restricted research use.
You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.
Aprotinin is a type of Antifibrinolytics
Antifibrinolytics belong to a vital category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the medical field. These compounds play a crucial role in preventing excessive bleeding by inhibiting the breakdown of blood clots. By promoting clot stability, antifibrinolytics help control bleeding, particularly in situations where there is a risk of uncontrolled hemorrhage.
One well-known antifibrinolytic agent is tranexamic acid, which is widely employed in various medical procedures, including surgery, trauma management, and dental procedures. This API works by binding to plasminogen, a protein involved in the dissolution of blood clots, and preventing its conversion to plasmin, the enzyme responsible for clot degradation.
Another prominent antifibrinolytic is aminocaproic acid, which acts in a similar manner to tranexamic acid. It competitively inhibits the activation of plasminogen, thereby preserving the integrity of formed clots.
Antifibrinolytics find applications in several medical specialties, such as orthopedics, cardiovascular surgery, and gynecology. They are particularly valuable in managing bleeding disorders, such as hemophilia and menorrhagia, as well as in minimizing blood loss during major surgical procedures.
As with any pharmaceutical API, the production and use of antifibrinolytics require adherence to strict quality control standards and regulatory guidelines to ensure their safety and efficacy. Healthcare professionals should carefully assess each patient's condition and consider potential contraindications or interactions before prescribing or administering antifibrinolytic medications.
In conclusion, antifibrinolytics play a crucial role in preventing excessive bleeding by inhibiting clot breakdown. These pharmaceutical APIs, such as tranexamic acid and aminocaproic acid, are widely used in various medical procedures and provide valuable therapeutic options for managing bleeding disorders and minimizing blood loss during surgeries.
Aprotinin manufacturers | traders | suppliers
We have 2 companies offering Aprotinin produced in 2 different countries.
Get in contact with the supplier of your choice:
- Kraeber & Co GmbH from Germany, product country of origin Germany
- Bayer from Germany, product country of origin Unknown
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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