Cinnamyl alcohol API Manufacturers
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Looking for Cinnamyl alcohol API 4407-36-7?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Cinnamyl alcohol. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Cinnamyl alcohol
- Synonyms:
- (2E)-3-phenylprop-2-en-1-ol , (E)-cinnamyl alcohol , Styrylcarbinol
- Cas Number:
- 4407-36-7
- DrugBank number:
- DB14186
- Unique Ingredient Identifier:
- SS8YOP444F
General Description:
Cinnamyl alcohol, identified by CAS number 4407-36-7, is a notable compound with significant therapeutic applications. Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as within commercial products. Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% . Sensitivity to cinnamyl alcohol may be identified with a clinical patch test.
Indications:
This drug is primarily indicated for: Cinnamyl alcohol is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Metabolism:
Cinnamyl alcohol undergoes metabolic processing primarily in: In general, esters containing an aromatic ring system are expected to be hydrolyzed in vivo. Cinnamyl alcohol is hydrolyzed to . This metabolic pathway ensures efficient processing of the drug, helping to minimize potential toxicity and side effects.
Absorption:
The absorption characteristics of Cinnamyl alcohol are crucial for its therapeutic efficacy: Cinnamyl alcohol is 66% absorbed through the skin and shown to be rapidly absorbed from the gut . The drug's ability to rapidly penetrate into cells ensures quick onset of action.
Route of Elimination:
The elimination of Cinnamyl alcohol from the body primarily occurs through: Cinnamyl alcohol is metabolized and excreted primarily in the urine and, to a minor extent, in the feces . After oral or intraperitoneal administration to rats and mice, 76–77% of the dose of cinnamyl alcohol was recovered in the urine and feces within 24 h . Understanding this pathway is essential for assessing potential drug accumulation and toxicity risks.
Categories:
Cinnamyl alcohol is categorized under the following therapeutic classes: Alcohols, Cell-mediated Immunity, Drugs that are Mainly Renally Excreted, Increased Histamine Release, Standardized Chemical Allergen. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Cinnamyl alcohol is a type of Dental and Oral Agents
Dental and oral agents belong to the pharmaceutical API category, playing a crucial role in oral health care. These agents are specifically designed to address various dental and oral conditions, ranging from tooth decay and gum diseases to oral infections and inflammation.
One of the primary types of dental and oral agents is antimicrobial APIs. These active pharmaceutical ingredients are known for their ability to inhibit the growth of bacteria and fungi in the oral cavity, helping to prevent and treat infections. Common antimicrobial APIs used in dental and oral care include chlorhexidine, cetylpyridinium chloride, and triclosan.
Another important category is analgesic APIs, which provide pain relief in dental and oral procedures. These agents work by blocking pain signals and reducing inflammation. Popular analgesic APIs in dental care include lidocaine, benzocaine, and ibuprofen.
Fluoride APIs are widely used in dental products to strengthen tooth enamel and prevent tooth decay. These APIs aid in remineralization, making teeth more resistant to acid attacks from bacteria and sugary foods.
Furthermore, there are APIs specifically formulated for treating specific oral conditions such as dry mouth or halitosis. These agents help restore moisture in the mouth and neutralize odor-causing compounds.
Dental and oral agents are typically formulated into various dosage forms, including mouthwashes, toothpaste, gels, and oral sprays. These formulations ensure convenient and effective delivery of the APIs to the affected areas in the oral cavity.
In summary, dental and oral agents are a vital component of oral health care, offering antimicrobial, analgesic, remineralizing, and specific therapeutic benefits. Incorporating these pharmaceutical APIs into dental products helps individuals maintain optimal oral health and prevent dental problems.
