Polyvinyl alcohol API Manufacturers

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Looking for Polyvinyl alcohol API 9002-89-5?

Description:
Here you will find a list of producers, manufacturers and distributors of Polyvinyl alcohol. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Polyvinyl alcohol 
Synonyms:
Alcohol polivinílico , PVOH  
Cas Number:
9002-89-5 
DrugBank number:
DB11060 
Unique Ingredient Identifier:
532B59J990

General Description:

Polyvinyl alcohol, identified by CAS number 9002-89-5, is a notable compound with significant therapeutic applications. Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .

Indications:

This drug is primarily indicated for: For use as a lubricant to prevent further irritation or to relieve dryness of the eye(s) . Its use in specific medical scenarios underscores its importance in the therapeutic landscape.

Absorption:

The absorption characteristics of Polyvinyl alcohol are crucial for its therapeutic efficacy: Polyvinyl alcohol is poorly absorbed from gastrointestinal tract, and readily eliminated from the body . The drug's ability to rapidly penetrate into cells ensures quick onset of action.

Half-life:

The half-life of Polyvinyl alcohol is an important consideration for its dosing schedule: When injected intravenously, polyvinyl alcohol has a half-life of 90 min . Intraocularly, in eye drop form, the half-life is 7.2 minutes . This determines the duration of action and helps in formulating effective dosing regimens.

Volume of Distribution:

Polyvinyl alcohol is distributed throughout the body with a volume of distribution of: This drug does not accumulate in the body when administered orally . This metric indicates how extensively the drug permeates into body tissues.

Pharmacodynamics:

Polyvinyl alcohol exerts its therapeutic effects through: Temporarily relieves burning and irritation due to dryness of the eye or from exposure to wind or sun. Lubricates the eyes and helps protect against further eye irritation/dryness . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.

Mechanism of Action:

Polyvinyl alcohol functions by: As a synthetic resin with hydrophilic properties, it increases the persistence of tear film and therefore lubricates and soothes dry/irritated eyes . This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.

Toxicity:

Categories:

Polyvinyl alcohol is categorized under the following therapeutic classes: Alcohols, Alkenes, Artificial Tears, Compounds used in a research, industrial, or household setting, EENT Drugs, Miscellaneous, Hydrocarbons, Acyclic, Macromolecular Substances, Plastics, Polymers, Polyvinyls, Vinyl Compounds. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Experimental Properties:

Further physical and chemical characteristics of Polyvinyl alcohol include:

  • Water Solubility: soluble in water (slightly)

Polyvinyl alcohol is a type of Dental and Oral Agents


Dental and oral agents belong to the pharmaceutical API category, playing a crucial role in oral health care. These agents are specifically designed to address various dental and oral conditions, ranging from tooth decay and gum diseases to oral infections and inflammation.

One of the primary types of dental and oral agents is antimicrobial APIs. These active pharmaceutical ingredients are known for their ability to inhibit the growth of bacteria and fungi in the oral cavity, helping to prevent and treat infections. Common antimicrobial APIs used in dental and oral care include chlorhexidine, cetylpyridinium chloride, and triclosan.

Another important category is analgesic APIs, which provide pain relief in dental and oral procedures. These agents work by blocking pain signals and reducing inflammation. Popular analgesic APIs in dental care include lidocaine, benzocaine, and ibuprofen.

Fluoride APIs are widely used in dental products to strengthen tooth enamel and prevent tooth decay. These APIs aid in remineralization, making teeth more resistant to acid attacks from bacteria and sugary foods.

Furthermore, there are APIs specifically formulated for treating specific oral conditions such as dry mouth or halitosis. These agents help restore moisture in the mouth and neutralize odor-causing compounds.

Dental and oral agents are typically formulated into various dosage forms, including mouthwashes, toothpaste, gels, and oral sprays. These formulations ensure convenient and effective delivery of the APIs to the affected areas in the oral cavity.

In summary, dental and oral agents are a vital component of oral health care, offering antimicrobial, analgesic, remineralizing, and specific therapeutic benefits. Incorporating these pharmaceutical APIs into dental products helps individuals maintain optimal oral health and prevent dental problems.