Doripenem API Manufacturers
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Established in: 2005
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Looking for Doripenem API ?
- Description:
- Here you will find a list of producers, manufacturers and traders of Doripenem. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Doripenem
- Synonyms:
- Cas Number:
- DrugBank number:
- DB06211
- Unique Ingredient Identifier:
- BHV525JOBH
About Doripenem
So, what does it do? Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an increased risk of death and lower clinical cure rates, resulting in a premature termination of the trial.
The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated pneumonia and to reiterate its safety and efficacy for its approved indications.
Ask the supplier for a certificate of analysis to find out more about the quality of Doripenem.
Doripenem is a type of Carbapenems
Carbapenems are a subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the field of medicine. These powerful antibiotics are highly effective against a broad spectrum of bacteria, including multidrug-resistant strains. Carbapenems exhibit a unique molecular structure that makes them resistant to enzymatic degradation by most β-lactamases, enzymes produced by bacteria to break down β-lactam antibiotics.
Carbapenems work by inhibiting bacterial cell wall synthesis, leading to cell lysis and ultimately killing the bacteria. They are administered intravenously or intramuscularly and are often reserved for serious infections caused by bacteria resistant to other antibiotics.
Some commonly used carbapenems include imipenem, meropenem, and doripenem. These drugs are prescribed in hospitals for the treatment of severe infections such as complicated urinary tract infections, intra-abdominal infections, and pneumonia.
It is important to note that the use of carbapenems should be carefully monitored due to the emergence of carbapenem-resistant bacteria. The overuse or misuse of these antibiotics can contribute to the development of drug-resistant strains, posing a significant challenge in healthcare settings.
In conclusion, carbapenems are a vital subcategory of pharmaceutical APIs used to combat bacterial infections. Their unique molecular structure and broad-spectrum activity make them effective against various drug-resistant bacteria. However, responsible use and surveillance are crucial to prevent the emergence of resistant strains and ensure the continued efficacy of these important antibiotics.
Doripenem (Carbapenems), classified under Antibacterials
Antibacterials, a category of pharmaceutical active pharmaceutical ingredients (APIs), play a crucial role in combating bacterial infections. These APIs are chemical compounds that target and inhibit the growth or kill bacteria, helping to eliminate harmful bacterial pathogens from the body.
Antibacterials are essential for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and more. They are commonly prescribed by healthcare professionals to combat both mild and severe bacterial infections.
Within the category of antibacterials, there are different classes and subclasses of APIs, each with distinct mechanisms of action and target bacteria. Some commonly used antibacterials include penicillins, cephalosporins, tetracyclines, macrolides, and fluoroquinolones. These APIs work by interfering with various aspects of bacterial cellular processes, such as cell wall synthesis, protein synthesis, DNA replication, or enzyme activity.
The development and production of antibacterial APIs require stringent quality control measures to ensure their safety, efficacy, and purity. Pharmaceutical manufacturers must adhere to Good Manufacturing Practices (GMP) and follow rigorous testing protocols to guarantee the quality and consistency of these APIs.
As bacterial resistance to antibiotics continues to be a significant concern, ongoing research and development efforts aim to discover and develop new antibacterial APIs. The evolution of antibacterials plays a crucial role in combating emerging bacterial strains and ensuring effective treatment options for infectious diseases.
In summary, antibacterials are a vital category of pharmaceutical APIs used to treat bacterial infections. They are designed to inhibit or kill bacteria, and their development requires strict adherence to quality control standards. By continually advancing research in this field, scientists and pharmaceutical companies can contribute to the ongoing battle against bacterial infections.
Doripenem manufacturers | traders | suppliers
We have 4 companies offering Doripenem produced in 3 different countries.
Get in contact with the supplier of your choice:
- LGM Pharma from United States, product country of origin World
- Xiamen Fine Chemical from China, product country of origin China
- Unimark Remedies from India, product country of origin India
- Beijing Lunarsun Pharma from China, product country of origin China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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