Ecallantide API Manufacturers
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Looking for Ecallantide API 460738-38-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Ecallantide. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Ecallantide
- Cas Number:
- 460738-38-9
- DrugBank number:
- DB05311
- Unique Ingredient Identifier:
- 5Q6TZN2HNM
About Ecallantide
It's time for some technical information for the ones who understand chemistry: Ecallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema. Ecallantide is a recombinant 60-amino-acid protein produced in Pichia pastoris yeast cells that contains three intramolecular disulfide bonds. It was discovered by phage display technology It shares sequence similarities with the naturally occurring human protein tissue-factor pathway inhibitor (TFPI), which is also known lipoprotein-associated coagulation inhibitor (LACI) The amino acid sequence of two compounds differ by seven amino acids Ecallantide works by blocking kallikrein to participate in the kallikrein-kinin system, which is a complex proteolytic cascade that initiates inflammatory and coagulation pathways.
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