Tofacitinib API Manufacturers

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TOP RANKING

Located in:

China

Produced in:

China

Established in: 1987

MOQ: 1 kg

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CEP

  • GMP

  • DMF

  • CoA

  • ISO9001

  • MSDS

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TOP RANKING

Located in:

France

Producer

Produced in:

Canada

Established in: 1952

MOQ: 25 kg

Employees: 550+

API manufacturing (Innovators, Generics and Highly Potent)

A tailor-made and flexible service approach

State-of-the-art analytical services including solid form and QbD laboratories

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

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  • DMF

  • BSE/TSE

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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2013

MOQ: 1 kg

Employees: 25+

ISO9001 certified

Drug R&D center (in Hangzhou)

From lab scale (mg/g) to commercial scale (kgs/tons)

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CEP

  • DMF

  • ISO9001

  • GMP

  • CoA

  • MSDS

  • BSE/TSE

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Produced in:

China

Established in: 2011

MOQ: 100 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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Replies in a day or 2

Producer

Produced in:

India

Established in: 1984

MOQ: -

Employees: 21,650

Diverse portfolio of 180+APIs

1754+ DMF across global markets

1100+ patents filed, and more than 70 own patents granted

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • WC

  • GMP

  • CoA

  • FDA

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  • BSE/TSE

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Located in:

China
  • CoA

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  • DMF

  • + 0

All certificates

  • coa

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Replies slower than most

Located in:

China

Producer

  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

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Replies slower than most

Located in:

India
  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

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  • DMF

  • CoA

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Replies slower than most

Located in:

China
  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

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  • coa

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Replies slower than most

Located in:

Spain

Producer

  • CoA

  • GMP

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  • DMF

  • + 0

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  • DMF

  • CoA

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Replies slower than most

Located in:

India

Producer

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  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • DMF

  • WC

  • CoA

Located in:

India
  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • WC

  • CoA

  • DMF

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

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Looking for Tofacitinib API 477600-75-2?

Description:
Here you will find a list of producers, manufacturers and traders of Tofacitinib. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Tofacitinib 
Synonyms:
Tofacitinibum , Tasocitinib  
Cas Number:
477600-75-2 
DrugBank number:
DB08895 
Unique Ingredient Identifier:
87LA6FU830

About Tofacitinib

Why are people looking for Tofacitinib? Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate.

You can ask the supplier for more technical information about the product.

Tofacitinib is a type of Immunosuppressants


Immunosuppressants are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a crucial role in medical treatments. These substances are designed to suppress or weaken the immune system's response, making them invaluable in various therapeutic applications.

Immunosuppressants find extensive use in the management of autoimmune diseases, organ transplantation, and the prevention of rejection reactions. By modulating the immune system's activity, these APIs help control excessive immune responses that can lead to tissue damage and chronic inflammation.

There are different classes of immunosuppressants, including corticosteroids, calcineurin inhibitors, antimetabolites, and biologics. Each class targets specific immune pathways to achieve the desired therapeutic effect. Corticosteroids, for instance, are known for their potent anti-inflammatory properties, making them effective in managing conditions such as rheumatoid arthritis and asthma.

Calcineurin inhibitors like cyclosporine and tacrolimus act by inhibiting the activity of calcineurin, a protein involved in immune cell activation. These drugs are commonly used in organ transplantation to prevent the immune system from attacking the transplanted organ.

Antimetabolites interfere with DNA synthesis and cell proliferation, thereby dampening immune responses. They are often prescribed for conditions like psoriasis and rheumatoid arthritis.

Biologic immunosuppressants, such as monoclonal antibodies, target specific immune cells or molecules involved in the disease process. They have revolutionized the treatment of autoimmune diseases like rheumatoid arthritis, Crohn's disease, and psoriasis.

Immunosuppressants require careful administration and monitoring due to their potential side effects and interactions with other medications. Close collaboration between healthcare professionals, pharmacists, and patients is essential to ensure the safe and effective use of these APIs in various therapeutic settings.

Overall, immunosuppressants represent a critical category of pharmaceutical APIs that significantly contribute to improving patients' quality of life by controlling the immune system's activity and managing various autoimmune conditions and transplantation outcomes.


Tofacitinib (Immunosuppressants), classified under Immunomodulators


Immunomodulators, a category of pharmaceutical active pharmaceutical ingredients (APIs), are substances that help regulate and modify the immune response of an individual. These compounds play a crucial role in treating various immune-related disorders and diseases. Immunomodulators work by either enhancing or suppressing the immune system, depending on the specific condition being treated.

Immunomodulators are used in the treatment of autoimmune disorders, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. By suppressing the immune system, these APIs help reduce the overactive immune response associated with these conditions, thereby alleviating symptoms and preventing further damage to the body's tissues.

On the other hand, immunomodulators are also employed to boost the immune system in cases of immunodeficiency disorders. These APIs stimulate the immune response, enabling the body to better fight off infections and diseases. Additionally, immunomodulators are utilized in the prevention and treatment of organ transplant rejection, where they help modulate the immune system to accept the transplanted organ.

The development and production of immunomodulators require rigorous testing and quality control to ensure their safety and efficacy. Pharmaceutical companies carefully formulate these APIs into various dosage forms, including tablets, capsules, injections, and topical preparations, to cater to different patient needs.

In summary, immunomodulators form a vital category of pharmaceutical APIs that regulate and modify the immune system. With their ability to modulate immune responses, these compounds contribute significantly to the management and treatment of various immune-related disorders and diseases, improving the quality of life for many patients.



Tofacitinib manufacturers | traders | suppliers

We have 14 companies offering Tofacitinib produced in 4 different countries.

Get in contact with the supplier of your choice:

  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Minakem from France, product country of origin Canada
  • Senova Technology Co., Ltd. from China, product country of origin China
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • Dr. Reddy's from India, product country of origin India
  • Hunan Ouya Biological Co., Ltd. from China, product country of origin China
  • Qilu Tianhe from China, product country of origin China
  • Unichem Labs. from India, product country of origin India
  • Beijing Lunarsun Pharma from China, product country of origin China
  • Sintenovo from Spain, product country of origin Spain
  • Micro Labs from India, product country of origin India
  • MSN Labs. from India, product country of origin India
  • Glenmark Pharma from India, product country of origin India
  • Sun Pharma from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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