Interferon alfacon-1 API Manufacturers
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Looking for Interferon alfacon-1 API 118390-30-0?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Interferon alfacon-1. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Interferon alfacon-1
- Synonyms:
- CIFN , consensus interferon , IFN Alfacon-1 , Interferon Consensus , Methionyl , methionyl interferon consensus , rCon-IFN , Recombinant Consensus Interferon
- Cas Number:
- 118390-30-0
- DrugBank number:
- DB00069
- Unique Ingredient Identifier:
- 56588OP40D
About Interferon alfacon-1
Do you want to know more about Interferon alfacon-1? You can find a small explanation about it here. Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the molecular construction, and a corresponding synthetic DNA sequence was constructed using chemical synthesis methodology.
Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of the amino acid positions. Interferon alfacon-1 is produced in Escherichia coli (E. coli) cells that have been genetically altered by insertion of a synthetically constructed sequence that codes for Interferon alfacon-1. Prior to final purification, Interferon alfacon-1 is allowed to oxidize to its native state, and its final purity is achieved by sequential passage over a series of chromatography columns. This protein has a molecular weight of 1934 daltons.
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