Ledipasvir | compare suppliers & send inquiries for free
Looking for Ledipasvir 1256388-51-8?
It's time for some technical information for the ones who understand chemistry: Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients Treatment options for chronic Hepatitis C have advanced significantly since 20 with the development of Direct Acting Antivirals (DAAs) such as ledipasvir. More specifically, ledipasvir is an inhibitor of the Hepatitis C Virus (HCV) Non-Structural Protein 5A (NS5A), which is required for viral RNA replication and assembly of HCV virions. Although its exact mechanism of action is unknown, it is postulated to prevent hyperphosphorylation of NS5A which is required for viral protein production.
It is effective against genotypes 1a, 1b, 4a, and 5a and with a lesser activity against genotypes 2a and 3a of HCV. Ledipasvir and other direct acting antivirals are very potent options for the treatment of Hepatitis C, as they exhibit a high barrier to the development of resistance This is an important advantage relative to HCV drugs that target other viral enzymes such as the protease, for which rapid development of resistance has proven to be an important cause of therapeutic failure.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.
Ledipasvir manufacturers | traders | suppliers
We have 8 companies offering Ledipasvir from 3 different countries.
Get in contact with the supplier of your choice:
- Maruti Futuristic Pharma Pvt Ltd from India
- Apino Pharma Co., Ltd. from China
- Mylan from India
- Shaoxing Hantai Pharma from China
- Natco Pharma from India
- PCAS from France
- Beijing Mesochem Technology Co Ltd from China
- Dalian Wista Pharma Co Ltd from China
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