Pemetrexed API Manufacturers
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Producer
Produced in:
Established in: 1989
MOQ: -
Employees: 5000+
6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO
R&D Centers with capabilities of ANDAs, DMFs and NDDS
462+ patents filed for drug substances and polymorphs
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Producer
Produced in:
Established in: 1984
MOQ: -
Employees: 21,650
Diverse portfolio of 180+APIs
1754+ DMF across global markets
1100+ patents filed, and more than 70 own patents granted
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Producer
Produced in:
Established in: 2018
MOQ: -
Employees: 200+
WHO GMP Approved sites for production
25+ years experience in manufacturing APIs for regulated markets
High quality product & superior client service
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Distributor
Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
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Producer
Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Producer
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MOQ: -
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Looking for Pemetrexed API 137281-23-3?
- Description:
- Here you will find a list of producers, manufacturers and traders of Pemetrexed. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pemetrexed
- Synonyms:
- Pemetrexed disodium heptahydrate
- Cas Number:
- 137281-23-3
- DrugBank number:
- DB00642
- Unique Ingredient Identifier:
- 04Q9AIZ7NO
About Pemetrexed
More information about the use of: Pemetrexed. Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery. Its use in non-small cell lung cancer has also been investigated.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements
Pemetrexed is a type of Antimetabolites
Antimetabolites are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various diseases, particularly cancer. These compounds are structurally similar to naturally occurring metabolites essential for cellular processes such as DNA and RNA synthesis. By mimicking these metabolites, antimetabolites interfere with the normal functioning of cellular pathways, leading to inhibition of cancer cell growth and proliferation.
One of the widely used antimetabolites is methotrexate, a folic acid antagonist that inhibits the enzyme dihydrofolate reductase, disrupting the production of DNA and RNA. This disruption impedes the growth of rapidly dividing cancer cells. Another common antimetabolite is 5-fluorouracil (5-FU), which inhibits the enzyme thymidylate synthase, thereby interfering with DNA synthesis and inhibiting cancer cell proliferation.
Antimetabolites can be classified into several subcategories based on their mechanism of action and chemical structure. These include purine and pyrimidine analogs, folic acid antagonists, and pyrimidine synthesis inhibitors. Examples of antimetabolites in these subcategories include azathioprine, cytarabine, and gemcitabine.
Despite their effectiveness, antimetabolites can exhibit certain side effects due to their interference with normal cellular processes. These side effects may include gastrointestinal disturbances, myelosuppression (reduced production of blood cells), and hepatotoxicity.
In conclusion, antimetabolites are a vital category of pharmaceutical APIs used in the treatment of various diseases, especially cancer. By mimicking natural metabolites and disrupting crucial cellular processes, these compounds effectively inhibit cancer cell growth and proliferation. However, their usage should be carefully monitored due to potential side effects.
Pemetrexed manufacturers | traders | suppliers
We have 27 companies offering Pemetrexed produced in 5 different countries.
Get in contact with the supplier of your choice:
- Shilpa Medicare Ltd from India, product country of origin India
- Dr. Reddy's from India, product country of origin India
- Gonane Pharma from India, product country of origin India
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Teva API from Israel, product country of origin Unknown
- Shanghai Jinhe Bio-Pharma from China, product country of origin China
- Chongqing Taihao from China, product country of origin China
- Adley Formulations from India, product country of origin India
- Acebright Pharma from India, product country of origin India
- Suzhou Lixin from China, product country of origin China
- Wuhan Calmland from China, product country of origin China
- Jiangsu Hansoh Pharma from China, product country of origin China
- Nippon Kayaku from Japan, product country of origin Japan
- Qilu Pharma from China, product country of origin China
- Laurus Labs from India, product country of origin India
- Mac Chem Products from India, product country of origin India
- Reliance Life Sciences from India, product country of origin India
- Huzhou Zhanwang from China, product country of origin China
- BrightGene from China, product country of origin China
- Qilu Antibiotics from China, product country of origin China
- Polymed Therapeutics from United States, product country of origin United States
- Emcure Pharma from India, product country of origin India
- MSN Labs. from India, product country of origin India
- Hetero Labs from India, product country of origin India
- Sun Pharma from India, product country of origin India
- Cipla from India, product country of origin India
- Mylan from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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