Pirbuterol API Manufacturers
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Looking for Pirbuterol API 38677-81-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Pirbuterol. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pirbuterol
- Synonyms:
- Maxair autohaler , Pirbuterol , Pirbuterolum
- Cas Number:
- 38677-81-5
- DrugBank number:
- DB01291
- Unique Ingredient Identifier:
- OG645J8RVW
About Pirbuterol
It's time for some technical information for the ones who understand chemistry: Pirbuterol is a beta-2 adrenergic bronchodilator. In vitro studies and in vivo pharmacologic studies have demonstrated that pirbuterol has a preferential effect on beta-2 Adrenergic receptors compared with isoproterenol. While it is recognized that beta-2 adrenergic receptors are the predominant receptors in bronchial smooth muscle, data indicate that there is a population of beta-2 receptors in the human heart, existing in a concentration between 10-50%. The precise function of these receptors has not been established.
The pharmacologic effects of beta adrenergic agonist drugs, including pirbuterol, are at least in proof attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (AlP) to cyclic-3† †-adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
You can ask the supplier for more technical information about the product.
