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Some technical information about this product: In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth muscle relaxation and vasodilation that subsequently facilitates relief in pulmonary arterial hypertension and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows it to grow in size and become erect and rigid Interestingly enough, it is precisely via this mechanism why sildenafil was at first researched as a potential treatment for angina - or chest pain associated with inadequate blood flow to the heart - before being serendipitously indicated for treating erectile dysfunction in the late 1980s.
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Sildenafil manufacturers | traders | suppliers
We have 16 companies offering Sildenafil from 6 different countries.
Get in contact with the supplier of your choice:
- Xi'an Tian Guangyuan Biotech Co.,Ltd from China
- SMS Pharma from India
- Hetero Drugs from India
- Aurobindo from India
- Mylan from India
- Dr. Reddy's from India
- Cadila Pharma from India
- Polpharma from Poland
- Amoli Organics from India
- Macleods Pharma from India
- Teva API from Israel
- Torrent Pharma from India
- Raks Pharma from India
- KRKA from Slovenia
- Signa from Mexico
- MSN Organics from India
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