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Looking for Sulindac 38194-50-2?
- API | Excipient name:
- Clinoril , Sulindac , Sulindaco , Sulindacum
- Cas Number:
- DrugBank number:
- Unique Ingredient Identifier:
You can find a short description about Sulindac here. Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo to an active sulfide compound by liver enzymes.
There is evidence from some studies that sulindac may be associated with fewer gastrointestinal side effects than other NSAIDs, except for the cyclooxygenase-2 (COX-2) inhibitor drug class. This may be due to the sulfide metabolite undergoing enterohepatic circulation thus maintaining constant blood levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and then reabsorbed from the intestines. While its full mechanism of action is not fully understood, sulindac is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and COX-2.
Check who is selling Sulindac in the overview above.
Sulindac manufacturers | traders | suppliers
We have 5 companies offering Sulindac from 2 different countries.
Get in contact with the supplier of your choice:
- Fabbrica Italiana Sintetici (FIS) from Italy
- Dr. Reddy's from India
- Piramal Healthcare from United Kingdom
- Olon from Italy
- Piramal Pharma Solutions from India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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