Dolutegravir API Manufacturers
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Country of origin
Established in: 2011
MOQ: 1 g
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Willingness To Start From Small
Flexible Payment Terms
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Looking for Dolutegravir API 1051375-16-6?
- Here you will find a list of producers, manufacturers and traders of Dolutegravir. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Cas Number:
- DrugBank number:
- Unique Ingredient Identifier:
So, what does it do? Dolutegravir is a HIV-1 intergrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells which gives it an excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare and FDA approved on August 201. On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Dolutegravir is a type of Anti-HIV
The Anti-HIV category of pharmaceutical APIs comprises a range of active pharmaceutical ingredients (APIs) specifically designed to combat the human immunodeficiency virus (HIV). These APIs play a critical role in the development and production of antiretroviral drugs, which are used to treat HIV infections and prevent the progression to acquired immunodeficiency syndrome (AIDS).
Anti-HIV APIs work by targeting various stages of the HIV life cycle, inhibiting viral replication and reducing the viral load in the body. Some commonly used APIs in this category include nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), and integrase inhibitors (INIs).
NRTIs, such as tenofovir and emtricitabine, act by blocking the reverse transcriptase enzyme, an essential component in the replication of the virus. NNRTIs, such as efavirenz and nevirapine, bind to the reverse transcriptase enzyme, preventing its proper functioning. PIs, like ritonavir and atazanavir, inhibit the protease enzyme, crucial for viral maturation and assembly. INIs, such as raltegravir and dolutegravir, target the integrase enzyme, impeding viral integration into the host's DNA.
These APIs are carefully synthesized and undergo rigorous quality testing to ensure their safety, efficacy, and compliance with regulatory standards. Pharmaceutical companies utilize these APIs as key building blocks to formulate antiretroviral medications, which are then prescribed to individuals living with HIV/AIDS worldwide.
Overall, the Anti-HIV API category plays a vital role in the ongoing battle against HIV/AIDS, offering effective treatment options and improved quality of life for patients affected by this challenging condition.
Dolutegravir manufacturers | traders | suppliers
We have 14 companies offering Dolutegravir from 2 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China
- Shanghai Acebright from China
- Shanghai Desano Chem. from China
- Hangzhou Coben Pharmaceutical Co Ltd from China
- Lupin from India
- Laurus Labs from India
- Hetero Labs from India
- Mylan from India
- MSN Life Sciences from India
- Micro Labs from India
- Emcure Pharma from India
- Cipla from India
- Lek Pharma from Slovenia
- Aurobindo from India
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