Heparin sodium
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Located in:

Denmark

Produced in:

Italy

Established in: 1885

MOQ: -

Employees: 150

Trusted for 140 years

Global distribution business with API manufacturing facilities

European company with presence in 3 continents

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Located in:

China

Produced in:

China

Established in: 2019

MOQ: 1 kg

Employees: 10+

Focused on pharmaceutical industry

Reasonable price for the customers

Full service from R&D stage to commercial stage

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Located in:

Spain

Distributor

Produced in:

European Union

Established in: 1993

MOQ: 15 kg

Employees: 700+

We can develop new APIs upon request

GMP, EMA/FDA, OSHAS cert. CDMO

12 local offices, strategically around the world

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Produced in:

China

Established in: 1990

MOQ: -

Employees: 3,000+

More than 200,000 customers

Custom packing sizes possible

GMP and GDP certified

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Produced in:

Italy

Established in: 1968

MOQ: 125 mu

Employees: 50+

Warehouse stock of nearly all APIs

GMP, GDP and ISO certified

Customisable (small-sized) packages

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Looking for Heparin sodium 9005-49-6?

Description:
Here you will find a list of producers, manufacturers and traders of Heparin sodium. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Heparin sodium 
Synonyms:
Calciparine , Eparina , Hep-lock , Heparinate , Heparinic acid , Liquaemin , Panheprin , Unfractionated heparin , Heparinum , Heparin sodium For parenteral preparations , Heparin , Heparinum natricum  
Cas Number:
9005-49-6 
DrugBank number:
DB01109 
Unique Ingredient Identifier:
4QW4AN84NQ

About Heparin sodium

Here is a short description about Heparin. Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa.

UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.

More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.

Heparin sodium is a type of Anticoagulant proteins


Anticoagulant proteins are a crucial subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a vital role in preventing the formation of blood clots. These proteins are naturally occurring substances that interfere with the clotting cascade, a complex series of reactions that lead to blood coagulation.

One of the well-known anticoagulant proteins is hirudin, derived from leeches. Hirudin acts by inhibiting thrombin, a key enzyme involved in blood clot formation. Another notable anticoagulant protein is antithrombin III, which blocks several clotting factors, including thrombin and factors IXa, Xa, XIa, and XIIa. These proteins are widely used in the pharmaceutical industry to develop medications for conditions such as deep vein thrombosis, pulmonary embolism, and stroke prevention.

The production of anticoagulant proteins involves advanced biotechnological processes. Recombinant DNA technology and genetic engineering techniques are employed to produce these proteins in large quantities. The proteins are expressed in host organisms such as bacteria, yeast, or mammalian cells, and then purified through various chromatographic and filtration steps to obtain a highly pure and active form.

The development of anticoagulant proteins has significantly improved the treatment and management of thrombotic disorders. These APIs have proven to be effective in preventing clot formation, reducing the risk of life-threatening complications. However, it is crucial to administer anticoagulant proteins under medical supervision due to their potential side effects and the need for precise dosing.

In conclusion, anticoagulant proteins are a vital subcategory of pharmaceutical APIs that act by inhibiting key components of the clotting cascade. Their production involves advanced biotechnological processes, and they have greatly enhanced the management of thrombotic disorders. Proper medical guidance is essential for their safe and effective use.


Heparin sodium (Anticoagulant proteins), classified under Anticoagulants


Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.

There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.

Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.

While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.

In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.



Heparin sodium manufacturers | traders | suppliers

We have 26 companies offering Heparin sodium from 9 different countries.

Get in contact with the supplier of your choice:

  • Chr. Olesen Group from Denmark
  • Apino Pharma Co., Ltd. from China
  • SUANFARMA from Spain
  • Fagron Industry from Belgium
  • Duchefa Farma B.V. from Netherlands
  • Nanjing King-Friend BC from China
  • API Corp. from Japan
  • Shandong Chen Zhong from China
  • Leo Pharma from Denmark
  • Opocrin S-C Plant from Italy
  • Lab. Derivati Organici from Italy
  • Yino Pharma from China
  • Gland Pharma from India
  • Hubei Enoray  from China
  • Scientific Protein Labs. from United States
  • Bioiberica from Spain
  • Hebei Changshan Bio. from China
  • Changzhou Qianhong from China
  • Qingdao Jiulong from China
  • Biofer from Italy
  • Sandoz from Austria
  • Shenzhen Hepalink from China
  • Dongying Tiandong Pharmaceutical Co Ltd from China
  • Sanofi from France
  • Shaoxing Hantai Pharma from China
  • Yantai Dongcheng Bio. from China

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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