Follow this page and receive notifications about new suppliers
Pemetrexed disodium heptahydrate (Pemetrexed) API Manufacturers
compare suppliers & get competitive offers
Filters
Reset
Selected filters:
Type
Production region
Qualifications
Country of origin
Producer
Produced in:
Established in: 1989
MOQ: -
Employees: 5000+
6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO
R&D Centers with capabilities of ANDAs, DMFs and NDDS
462+ patents filed for drug substances and polymorphs
+ 0
All certificates
Distributor
Produced in:
Established in: 1987
MOQ: 1 kg
Employees: 50+
Passed ISO9001:2015 and SGS audit
Provide one-stop CDMO service from R&D to production
Specialized in APIs & Pharmaceutical Intermediates for 37 years
+ 0
All certificates
Producer
Produced in:
Established in: 2018
MOQ: -
Employees: 200+
WHO GMP Approved sites for production
25+ years experience in manufacturing APIs for regulated markets
High quality product & superior client service
+ 0
All certificates
Distributor
Produced in:
Established in: 2019
MOQ: 1 kg
Employees: 10+
Focused on pharmaceutical industry
Reasonable price for the customers
Full service from R&D stage to commercial stage
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Distributor
Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
Produced in:
Established in: 1984
MOQ: -
Employees: 21,650
Diverse portfolio of 180+APIs
1754+ DMF across global markets
1100+ patents filed, and more than 70 own patents granted
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
Producer
+ 0
All certificates
How does it work?
You can register for free as long as you are registering on behalf of a legal company related to the pharmaceutical industry
Search in the search bar the product that you’re looking for. We’ll show you an overview of all available suppliers. Use the filters to select the relevant suppliers only
Have you found interesting suppliers? Then it’s time to contact them. Use the send inquiry button and send them a message. You can send for each product, 3 inquiries per week
Suppliers get notified by Pharmaoffer that they’ve received a new inquiry. They will come back to you with their questions, certificates, and offer in the chat on Pharmaoffer. We will send you an email in case of any news
Does the supplier meet your quality and commercial requirements? Then you can place the order. Just follow the steps of our order module
Looking for Pemetrexed API 137281-23-3?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Pemetrexed. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pemetrexed
- Synonyms:
- Pemetrexed disodium heptahydrate
- Cas Number:
- 137281-23-3
- DrugBank number:
- DB00642
- Unique Ingredient Identifier:
- 04Q9AIZ7NO
About Pemetrexed
More information about the use of: Pemetrexed. Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery. Its use in non-small cell lung cancer has also been investigated.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements
Pemetrexed is a type of Antimetabolites
Antimetabolites are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various diseases, particularly cancer. These compounds are structurally similar to naturally occurring metabolites essential for cellular processes such as DNA and RNA synthesis. By mimicking these metabolites, antimetabolites interfere with the normal functioning of cellular pathways, leading to inhibition of cancer cell growth and proliferation.
One of the widely used antimetabolites is methotrexate, a folic acid antagonist that inhibits the enzyme dihydrofolate reductase, disrupting the production of DNA and RNA. This disruption impedes the growth of rapidly dividing cancer cells. Another common antimetabolite is 5-fluorouracil (5-FU), which inhibits the enzyme thymidylate synthase, thereby interfering with DNA synthesis and inhibiting cancer cell proliferation.
Antimetabolites can be classified into several subcategories based on their mechanism of action and chemical structure. These include purine and pyrimidine analogs, folic acid antagonists, and pyrimidine synthesis inhibitors. Examples of antimetabolites in these subcategories include azathioprine, cytarabine, and gemcitabine.
Despite their effectiveness, antimetabolites can exhibit certain side effects due to their interference with normal cellular processes. These side effects may include gastrointestinal disturbances, myelosuppression (reduced production of blood cells), and hepatotoxicity.
In conclusion, antimetabolites are a vital category of pharmaceutical APIs used in the treatment of various diseases, especially cancer. By mimicking natural metabolites and disrupting crucial cellular processes, these compounds effectively inhibit cancer cell growth and proliferation. However, their usage should be carefully monitored due to potential side effects.
Pemetrexed manufacturers | traders | suppliers
We have 28 companies offering Pemetrexed produced in 5 different countries.
Get in contact with the supplier of your choice:
- Shilpa Medicare Ltd from India, product country of origin India
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Gonane Pharma from India, product country of origin India
- Apino Pharma Co., Ltd. from China, product country of origin China
- Acebright Pharma from India, product country of origin India
- Chongqing Taihao from China, product country of origin China
- Wuhan Calmland from China, product country of origin China
- Shanghai Jinhe Bio-Pharma from China, product country of origin China
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Mac Chem Products from India, product country of origin India
- Polymed Therapeutics from United States, product country of origin United States
- Laurus Labs from India, product country of origin India
- Nippon Kayaku from Japan, product country of origin Japan
- Reliance Life Sciences from India, product country of origin India
- Suzhou Lixin from China, product country of origin China
- Adley Formulations from India, product country of origin India
- Qilu Antibiotics from China, product country of origin China
- Teva API from Israel, product country of origin Unknown
- Huzhou Zhanwang from China, product country of origin China
- BrightGene from China, product country of origin China
- Jiangsu Hansoh Pharma from China, product country of origin China
- Dr. Reddy's from India, product country of origin India
- Mylan from India, product country of origin India
- Sun Pharma from India, product country of origin India
- Hetero Labs from India, product country of origin India
- Cipla from India, product country of origin India
- Emcure Pharma from India, product country of origin India
- MSN Labs. from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
You can use the filters to find high-quality suppliers. For example, you can select GMP, FDA or ISO certified suppliers. Visit our FAQ page or use the chat box in the corner to get more information about Pharmaoffer.