Chlorthalidone API Manufacturers

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Located in:

Spain

Produced in:

Spain

Established in: 1970

MOQ: -

Employees: 80+

2 Spanish GMP-certified plants

Over 400m³ reactor vessel capacity

Highly professional & care for ethical values

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CEP

  • ISO

  • WHO-GMP

  • GMP

  • DMF

  • MSDS

  • CoA

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Replies quickly

Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

  • MSDS

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Located in:

India
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  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

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Replies slower than most

Located in:

India
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  • GMP

  • CEP

  • FDA

  • DMF

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  • CEP

  • GMP

  • DMF

  • CoA

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Replies slower than most

Located in:

India
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  • GMP

  • CEP

  • FDA

  • DMF

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  • DMF

  • CoA

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Replies slower than most

Located in:

Italy

Producer

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  • DMF

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  • FDA

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Located in:

India
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  • GMP

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  • WC

  • CoA

  • DMF

  • GMP

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Replies slower than most

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

  • GMP

  • DMF

  • WC

  • FDA

  • KDMF

  • CEP

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

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Looking for Chlorthalidone API 77-36-1?

Description:
Here you will find a list of producers, manufacturers and traders of Chlorthalidone. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Chlorthalidone 
Synonyms:
Chlorphthalidolone , Chlortalidone , Chlorthalidone , Phthalamodine , Phthalamudine  
Cas Number:
77-36-1 
DrugBank number:
DB00310 
Unique Ingredient Identifier:
Q0MQD1073Q

About Chlorthalidone

Want to know what Chlorthalidone is used for? Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule cells in the kidney. The exact mechanism of chlorthalidone's anti-hypertensive effect is under debate, however, it is thought that increased diuresis results in decreased plasma and extracellular fluid volume, decreased cardiac output and therefore overall reduction in blood pressure. Chlorthalidone is considered first-line therapy for management of uncomplicated hypertension as there is strong evidence from meta-analyses that thiazide diuretics such as chlorthalidone reduce the risk of stroke, myocardial infarction, heart failure, and cardiovascular all-cause mortality in patients with hypertension.

Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.

Chlorthalidone is a type of Diuretics


Diuretics, a subcategory of pharmaceutical active pharmaceutical ingredients (APIs), are compounds commonly used in the treatment of conditions such as hypertension, congestive heart failure, and edema. Diuretics, also known as water pills, function by increasing the production of urine, thereby promoting the excretion of excess water and electrolytes from the body.

There are several types of diuretics, including thiazide diuretics, loop diuretics, and potassium-sparing diuretics. Thiazide diuretics, such as hydrochlorothiazide, work by inhibiting the reabsorption of sodium and chloride in the kidneys, leading to increased urine production. Loop diuretics, such as furosemide, act on the loop of Henle in the kidneys to block the reabsorption of sodium and chloride, resulting in a more potent diuretic effect. Potassium-sparing diuretics, like spironolactone, help retain potassium in the body while still promoting diuresis.

These diuretic APIs are widely used in the pharmaceutical industry to formulate medications that effectively manage fluid retention and related conditions. They are available in various forms, including tablets, capsules, and intravenous formulations. Diuretics are often prescribed as part of combination therapies to enhance their effectiveness and minimize adverse effects.

It is important to note that the use of diuretics should be closely monitored by healthcare professionals due to potential side effects such as electrolyte imbalances, dehydration, and hypotension. Proper dosage and patient-specific considerations are crucial to ensure optimal therapeutic outcomes.

In conclusion, diuretics are a vital subcategory of pharmaceutical APIs used to treat conditions characterized by fluid retention. Their mechanisms of action vary, but they all facilitate increased urine production, assisting the body in eliminating excess fluids. The proper use of diuretics, in combination with medical supervision, can effectively manage various cardiovascular and renal conditions.


Chlorthalidone (Diuretics), classified under Antihypertensive agents


Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.



Chlorthalidone manufacturers | traders | suppliers

We have 9 companies offering Chlorthalidone produced in 3 different countries.

Get in contact with the supplier of your choice:

  • Menadiona, S.L. from Spain, product country of origin Spain
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Chromo Labs. from India, product country of origin India
  • Maithri Drugs from India, product country of origin India
  • Unichem Labs. from India, product country of origin India
  • Euticals from Italy, product country of origin Unknown
  • Amoli Organics from India, product country of origin India
  • Ipca Labs. from India, product country of origin Unknown
  • Mylan from India, product country of origin India

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