Chlorthalidone | compare suppliers & send inquiries for free
Looking for Chlorthalidone 77-36-1?
Want to know what Chlorthalidone is used for? Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule cells in the kidney. The exact mechanism of chlorthalidone's anti-hypertensive effect is under debate, however, it is thought that increased diuresis results in decreased plasma and extracellular fluid volume, decreased cardiac output and therefore overall reduction in blood pressure. Chlorthalidone is considered first-line therapy for management of uncomplicated hypertension as there is strong evidence from meta-analyses that thiazide diuretics such as chlorthalidone reduce the risk of stroke, myocardial infarction, heart failure, and cardiovascular all-cause mortality in patients with hypertension.
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Chlorthalidone manufacturers | traders | suppliers
We have 11 companies offering Chlorthalidone from 3 different countries.
Get in contact with the supplier of your choice:
- TIEFENBACHER API + Ingredients from Germany
- Menadiona, S.L. from Spain
- Metrochem API from India
- Mylan from India
- Ipca Labs. from India
- Euticals from Italy
- Amoli Organics from India
- Macleods Pharma from India
- Maithri Drugs from India
- Unichem Labs. from India
- Chromo Labs. from India
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