Dihydroergocriptine Mesylate API Manufacturers

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Looking for Dihydroergocriptine Mesylate API 24730-10-7?

Here you will find a list of producers, manufacturers and distributors of Dihydroergocriptine Mesylate. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Dihydroergocriptine Mesylate 
Cas Number:
DrugBank number:
Unique Ingredient Identifier:

Dihydroergocriptine Mesylate is a type of Ergot alkaloids

Ergot alkaloids are a prominent category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that possess diverse medicinal properties. Derived from the fungus Claviceps purpurea, ergot alkaloids have been utilized for centuries in various therapeutic applications. These bioactive compounds exhibit vasoconstrictive, analgesic, and dopaminergic activities, making them valuable in the treatment of multiple medical conditions.

The primary medicinal use of ergot alkaloids lies in their efficacy in migraine management. Ergotamine and dihydroergotamine, two notable members of this category, are potent vasoconstrictors that alleviate migraine symptoms by narrowing blood vessels in the brain. These compounds also possess serotonin receptor agonist activity, further contributing to their therapeutic effect.

Furthermore, ergot alkaloids find application in obstetrics and gynecology. Ergometrine (ergonovine) and methylergometrine (methylergonovine) are commonly used to prevent and treat postpartum hemorrhage by promoting uterine contractions. Their ability to stimulate smooth muscle contraction makes them valuable in other gynecological procedures as well.

Despite their advantageous properties, ergot alkaloids require careful administration due to their potential side effects, including peripheral vasoconstriction and central nervous system disturbances. It is crucial for healthcare professionals to monitor dosage and usage to minimize adverse reactions.

In summary, ergot alkaloids represent a significant pharmaceutical API category with diverse applications in migraine management and obstetrics. Their potent bioactivity and historical significance contribute to their continued relevance in modern medicine.