Estrogens
Estrogens are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a crucial role in hormone therapy and women's health. Estrogens are a class of steroidal compounds that are primarily produced in the ovaries and play a significant role in the development and maintenance of female reproductive tissues and secondary sexual characteristics. These APIs are widely used in various pharmaceutical formulations, including oral contraceptives, hormone replacement therapies, and treatments for menopausal symptoms. They are also utilized in the management of conditions such as hypogonadism, infertility, and certain types of cancer.
Estrogens exert their effects by binding to estrogen receptors, which are present in various tissues throughout the body. This binding initiates a cascade of cellular and molecular events that regulate gene expression and modulate physiological processes.
Some common examples of estrogens used in pharmaceutical formulations include estradiol, estrone, and estriol. These compounds are typically synthesized from natural sources or derived from plant-based substances through a series of chemical reactions and purification processes.
As with any pharmaceutical API, the production of estrogens follows strict quality control guidelines to ensure purity, potency, and safety. Stringent regulatory standards and rigorous testing protocols are employed to guarantee consistent quality and adherence to pharmaceutical industry regulations.
In conclusion, estrogens are a vital subcategory of pharmaceutical APIs with a wide range of applications in women's health and hormone therapy. Their role in maintaining hormonal balance and addressing various medical conditions underscores their importance in modern medicine.
Name | CAS number | Category | Amount of suppliers |
---|---|---|---|
Conjugated Estrogens | 438-67-5 | Estrogens | 3 |
Cyclofenil | 2624-43-3 | Estrogens | 2 |
Diethylstilbestrol | 56-53-1 | Estrogens | 2 |
Estradiol | 50-28-2 | Estrogens | 23 |
Estradiol valerate | 979-32-8 | Estrogens | 8 |
Estriol | 50-27-1 | Estrogens | 6 |
Estrogens, esterified | Estrogens | 1 | |
Estrone | 53-16-7 | Estrogens | 5 |
Ethinyl Estradiol | 57-63-6 | Estrogens | 13 |
Ospemifene | 128607-22-7 | Estrogens | 8 |
Raloxifene | 84449-90-1 | Estrogens | 22 |