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Galantamine | compare suppliers & send inquiries for free

Here you will find a list of producers, manufacturers and traders of Galantamine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
Aurobindo


Type: Producer
Origin: India
India
Menovo

MOQ: 1 kg
Type: Producer
Origin: China
China
Dr. Reddy's


Type: Producer
Origin: India
India
Indena


Type: Producer
Origin: Italy
Italy
Macfarlan Smith


Type: Producer
Origin: United Kingdom
United Kingdom
Teva


Type: Producer
Origin: Israel
Israel
Jubilant Generics


Type: Producer
Origin: India
India
Scinopharm


Type: Producer
Origin: Taiwan
Taiwan
Teva (Czech)


Type: Producer
Origin: Czech Republic
Czech Republic
Zhejiang Yixin


Type: Producer
Origin: China
China
Sanochemia Pharma


Type: Producer
Origin: Austria
Austria

Looking for Galantamine 357-70-0?

API | Excipient name:
Galantamine 
Synonyms:
Galanthamine, Galantamine hydrobromide, Galantamine hydrobromide Produced by a synthetic process, Galantamine hydrobromide Isolated from natural sources  
Cas Number:
357-70-0 
DrugBank number:
DB00674 
Unique Ingredient Identifier:
0D3Q044KCA

About Galantamine

You can find a short description about Galantamine here. Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and postpolio paralytic conditions, and for reversal of neuromuscular blockade Following the discovery of its AChE-inhibiting properties, the cognitive effects of galantamine were studied in a wide variety of psychiatric disorders such as mild cognitive impairment, cognitive impairment in schizophrenia and bipolar disorder, and autism; however, re-development of the drug for Alzheimer’s disease did not commence until the early 1990s due to difficulties in extraction and synthesis.

Galantamine blocks the breakdown of acetylcholine in the synaptic cleft, thereby increasing acetylcholine neurotransmission. It also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance. The drug was approved by the FDA in 2001 for the treatment of mild to moderate dementia of the Alzheimer's type. As Alzheimer's disease is a progressive neurodegenerative disorder, galantamine is not known to alter the course of the underlying dementing process. Galantamine works to block the enzyme responsible for the breakdown of acetylcholine in the synaptic cleft, thereby enhancing cholinergic neuron function and signalling. Under this hypothesized mechanism of action, the therapeutic effects of galantamine may decrease as the disease progression advances and fewer cholinergic neurons remain functionally intact.

Ask the supplier for a certificate of analysis to find out more about the quality of Galantamine.

Galantamine manufacturers | traders | suppliers
We have 11 companies offering Galantamine from 4 different countries.

Get in contact with the supplier of your choice:

  • Aurobindo from India
  • Menovo from China
  • Indena from Italy
  • Dr. Reddy's from India
  • Jubilant Generics from India
  • Scinopharm from Taiwan
  • Teva from Israel
  • Macfarlan Smith from United Kingdom
  • Sanochemia Pharma from Austria
  • Teva (Czech) from Czech Republic
  • Zhejiang Yixin from China

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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