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    Galantamine | compare suppliers & send inquiries for free

    Here you will find a list of producers, manufacturers and traders of Galantamine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
    United Kingdom Macfarlan Smith
    Type: Producer
    Produced in: United Kingdom
    Unknown
    China Shandong Octagon Chemicals Limited

    MOQ: 100 g
    Type: Distributor
    Produced in: China
    China
    Taiwan Scinopharm
    Type: Producer
    Produced in: Taiwan
    Unknown
    India Jubilant Generics
    Type: Producer
    Produced in: India
    Unknown
    China Menovo
    Type: Producer
    Produced in: China
    China
    Austria Sanochemia Pharma
    Type: Producer
    Produced in: Austria
    Austria
    China Zhejiang Yixin
    Type: Producer
    Produced in: China
    China
    Czech Republic Teva API (Czech)
    Type: Producer
    Produced in: Czech Republic
    Unknown
    Belgium Janssen Pharma
    Type: Producer
    Produced in: Belgium
    Unknown
    Israel Teva API
    Type: Producer
    Produced in: Israel
    Unknown
    Italy Indena
    Type: Producer
    Produced in: Italy
    Unknown
    India Aurobindo
    Type: Producer
    Produced in: India
    Unknown
    India Dr. Reddy's
    Type: Producer
    Produced in: India
    India

    Looking for Galantamine 357-70-0?

    API | Excipient name:
    Galantamine 
    Synonyms:
    Galanthamine, Galantamine hydrobromide, Galantamine hydrobromide Produced by a synthetic process, Galantamine hydrobromide Isolated from natural sources  
    Cas Number:
    357-70-0 
    DrugBank number:
    DB00674 
    Unique Ingredient Identifier:
    0D3Q044KCA

    About Galantamine

    You can find a short description about Galantamine here. Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and postpolio paralytic conditions, and for reversal of neuromuscular blockade Following the discovery of its AChE-inhibiting properties, the cognitive effects of galantamine were studied in a wide variety of psychiatric disorders such as mild cognitive impairment, cognitive impairment in schizophrenia and bipolar disorder, and autism; however, re-development of the drug for Alzheimer’s disease did not commence until the early 1990s due to difficulties in extraction and synthesis.

    Galantamine blocks the breakdown of acetylcholine in the synaptic cleft, thereby increasing acetylcholine neurotransmission. It also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance. The drug was approved by the FDA in 2001 for the treatment of mild to moderate dementia of the Alzheimer's type. As Alzheimer's disease is a progressive neurodegenerative disorder, galantamine is not known to alter the course of the underlying dementing process. Galantamine works to block the enzyme responsible for the breakdown of acetylcholine in the synaptic cleft, thereby enhancing cholinergic neuron function and signalling. Under this hypothesized mechanism of action, the therapeutic effects of galantamine may decrease as the disease progression advances and fewer cholinergic neurons remain functionally intact.

    Ask the supplier for a certificate of analysis to find out more about the quality of Galantamine.

    Galantamine manufacturers | traders | suppliers
    We have 13 companies offering Galantamine from 4 different countries.

    Get in contact with the supplier of your choice:

    • Shandong Octagon Chemicals Limited from China
    • Aurobindo from India
    • Menovo from China
    • Indena from Italy
    • Dr. Reddy's from India
    • Scinopharm from Taiwan
    • Jubilant Generics from India
    • Macfarlan Smith from United Kingdom
    • Teva API from Israel
    • Sanochemia Pharma from Austria
    • Teva API (Czech) from Czech Republic
    • Janssen Pharma from Belgium
    • Zhejiang Yixin from China

    Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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