Imipramine | compare suppliers & send inquiries for free
Looking for Imipramine 50-49-7?
Here you will find more information about Imipramine. Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring.
In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Tertiary amine TCAs, such as imipramine and amitriptyline, are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and desipramine. TCAs also block histamine H1 receptors, Alpha-1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively Imipramine has less sedative and anticholinergic effects than the tertiary amine TCAs, amitriptyline and clomipramine. Imipramine may be used to treat depression and nocturnal enuresis in children. Unlabeled indications include chronic and neuropathic pain (including diabetic neuropathy), panic disorder, attention-deficit/hyperactivity disorder (ADHD), and post-traumatic stress disorder (PTSD)1.
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Imipramine manufacturers | traders | suppliers
We have 7 companies offering Imipramine from 4 different countries.
Get in contact with the supplier of your choice:
- Lupin from India
- R. L. Fine Chem from India
- Corden Pharma from Germany
- Shaoxing Hantai Pharma from China
- Teva from Israel
- Unnati Pharmaceuticals Pvt Ltd from India
- Lundbeck Pharma from Italy
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