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Looking for Lacidipine 103890-78-4?
- Description:
- Here you will find a list of producers, manufacturers and traders of Lacidipine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Lacidipine
- Synonyms:
- Cas Number:
- 103890-78-4
- DrugBank number:
- DB09236
- Unique Ingredient Identifier:
- 260080034N
About Lacidipine
Why are professionals looking for Lacidipine? Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure. Compared to other dihydropyridine calcium antagonists, lacidipine exhibits a greater antioxidant activity which may confer potentially beneficial antiatherosclerotic effects Lacidipine is a highly lipophilic molecule that interacts with the biological membranes. Through radiotracer analysis, it was determined that lacidipine displays a high membrane partition coefficient leading to accumulation of the drug in the membrane and slow rate of membrane washout When visualized by small-angle X-ray diffraction with angstrom resolution to examine its location within the membranes, lacidipine was found deep within the membrane's hydrocarbon core These results may explain the long clinical half-life of lacidipine In randomised, well-controlled trials, administration of daily single-dose lacidipine ranging from 2-6 mg demonstrated comparable antihypertensive efficacy similar to that of other long-acting dihydropyridine calcium antagonists, thiazide diuretics, atenolol (a beta-blocker) and enalapril (an ACE inhibitor).
Ask the supplier for a certificate of analysis to find out more about the quality of Lacidipine.
Lacidipine manufacturers | traders | suppliers
We have 6 companies offering Lacidipine from 4 different countries.
Get in contact with the supplier of your choice:
- LEBSA from Spain
- Cadila Pharma from India
- Glaxosmithkline from United Kingdom
- Unichem Labs. from India
- Dr. Reddy's from India
- Procos from Italy
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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