Letrozole API Manufacturers
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Established in: 1989
MOQ: -
Employees: 5000+
6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO
R&D Centers with capabilities of ANDAs, DMFs and NDDS
462+ patents filed for drug substances and polymorphs
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Expertise in Low Volume, High Value (LVHV) APIs
Technical knowledge for high-tech API production
therapeutic production sites with GMP compliance
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Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Engaged in the production of small molecule chemical drug APIs and preparations
Provide CDMO services for high-activity anti-tumor characteristic APIs
153-acre API and preparation production base
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Passed ISO9001:2015 and SGS audit
Provide one-stop CDMO service from R&D to production
Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification
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Portfolio of over 2,000 APIs
Precise quality control
End-to-end global regulatory support
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14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Looking for Letrozole API 112809-51-5?
- Description:
- Here you will find a list of producers, manufacturers and traders of Letrozole. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Letrozole
- Synonyms:
- Femara , Letrozol , Letrozole
- Cas Number:
- 112809-51-5
- DrugBank number:
- DB01006
- Unique Ingredient Identifier:
- 7LKK855W8I
About Letrozole
What can you use it for? Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990, It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements
Letrozole is a type of Aromatase inhibitors
Aromatase inhibitors (AIs) are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) commonly used in the treatment of hormone-sensitive conditions, including breast cancer and endometriosis. These compounds work by blocking the enzyme aromatase, which is responsible for the conversion of androgens into estrogens in peripheral tissues.
AIs are classified into two main types: steroidal and non-steroidal inhibitors. Steroidal AIs, such as exemestane, bind irreversibly to aromatase, while non-steroidal AIs, such as anastrozole and letrozole, inhibit aromatase activity reversibly. Both types effectively reduce estrogen levels, which is beneficial in hormone-driven cancers where estrogen promotes tumor growth.
The use of AIs in breast cancer treatment has significantly improved patient outcomes, particularly in postmenopausal women. By suppressing estrogen production, AIs prevent estrogen from fueling the growth of estrogen receptor-positive breast cancer cells. They are often prescribed as adjuvant therapy after surgery or as a first-line treatment for metastatic breast cancer.
Apart from their application in breast cancer, AIs have also shown efficacy in managing endometriosis, a painful condition where endometrial tissue grows outside the uterus. By reducing estrogen levels, AIs help alleviate symptoms and inhibit the growth of endometrial lesions.
Overall, aromatase inhibitors are vital components of modern pharmaceutical therapies targeting hormone-related diseases. Their ability to modulate estrogen levels through enzymatic inhibition has revolutionized the treatment landscape for breast cancer and endometriosis, improving patient prognosis and quality of life.
Letrozole (Aromatase inhibitors), classified under Hormonal Agents
Hormonal agents are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the medical field. These substances play a crucial role in regulating and modulating hormonal functions within the body. Hormonal agents are designed to mimic or manipulate the effects of naturally occurring hormones, allowing healthcare professionals to treat various endocrine disorders and hormonal imbalances.
Hormonal agents are commonly employed in the treatment of conditions such as hypothyroidism, hyperthyroidism, diabetes, and hormonal cancers. These APIs work by interacting with specific hormone receptors, either by stimulating or inhibiting their activity, to restore the balance of hormones in the body. They can be administered orally, intravenously, or through other routes depending on the specific medication and patient needs.
Pharmaceutical companies employ rigorous manufacturing processes and quality control measures to ensure the purity, potency, and safety of hormonal agent APIs. These APIs are synthesized using chemical or biotechnological methods, often starting from natural hormone sources or through recombinant DNA technology. Stringent regulatory guidelines are in place to guarantee the efficacy and safety of hormonal agent APIs, ensuring that patients receive high-quality medications.
As the demand for hormone-related therapies continues to grow, ongoing research and development efforts focus on enhancing the effectiveness and reducing the side effects of hormonal agent APIs. This includes the exploration of novel delivery systems, advanced formulations, and targeted drug delivery methods. By continuously advancing our understanding and capabilities in hormonal agents, the medical community can improve patient outcomes and quality of life for individuals with hormonal disorders.
Letrozole manufacturers | traders | suppliers
We have 23 companies offering Letrozole produced in 7 different countries.
Get in contact with the supplier of your choice:
- Shilpa Medicare Ltd from India, product country of origin India
- Tofigh Daru from Iran, product country of origin Iran
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Sichuan Elixir Pharmaceutical Co., Ltd from China, product country of origin China
- Sinoway industrial Co.,Ltd from China, product country of origin China
- LGM Pharma from United States, product country of origin World
- Natco Pharma from India, product country of origin India
- Jiangsu Hengrui from China, product country of origin China
- Finorga from France, product country of origin France
- ALCAMI from United States, product country of origin United States
- Actavis Group from Iceland, product country of origin Unknown
- Fujian South Pharma from China, product country of origin China
- Zhejiang Hisun Pharma from China, product country of origin China
- Mac Chem Products from India, product country of origin India
- Teva API from Israel, product country of origin Unknown
- USV from India, product country of origin India
- Fresenius Kabi Onc. from India, product country of origin India
- Humble Healthcaare from India, product country of origin India
- Ind-Swift Labs. from India, product country of origin India
- Hetero Labs from India, product country of origin India
- Sun Pharma from India, product country of origin India
- Cipla from India, product country of origin India
- Mylan from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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