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Melatonine (Melatonin)
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Distributor
Produced in:
Established in: 1987
MOQ: 1 kg
Employees: 50+
ISO 9001:2015 & SGS audited supplier
One-stop CDMO Solutions for APl and Key intermediates
Specialized in APIs & Pharmaceutical Intermediates for 37 years
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Producer
Produced in:
Established in: 2005
MOQ: 1 kg
Employees: 85
Strict quality control
15 years of experience in API production
Provide OEM & ODM service
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Producer
Produced in:
Established in: 2011
MOQ: 1 kg
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Distributor
Produced in:
Established in: 2005
MOQ: -
Employees: 200+
Portfolio of over 2,000 APIs
Precise quality control
End-to-end global regulatory support
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Distributor
Produced in:
Established in: 2019
MOQ: -
Employees: 50+
ISO 9001, SGS, Certificated supplier.
Audit available either on site or remote.
Professional One Stop Service for delivery to customers.
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Distributor
Produced in:
Established in: 1968
MOQ: 500 g
Employees: 50+
Warehouse stock of nearly all APIs
GMP, GDP and ISO certified
Customisable (small-sized) packages
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Producer
Produced in:
Established in: 1886
MOQ: -
Employees: 275+
Raw materials, CMO and OTC products
Two GMP certified locations
Customisable (small-sized) packages
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Producer
Produced in:
Established in: 2021
MOQ: -
Employees: 19
API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides
Small quantity APIs to commercial scale
GMP and USFDA certification based on quantity, order, assignment.
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Looking for Melatonin API 73-31-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Melatonin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Melatonin
- Synonyms:
- Melatonin , Melatonine , Melatoninum
- Cas Number:
- 73-31-4
- DrugBank number:
- DB01065
- Unique Ingredient Identifier:
- JL5DK93RCL
About Melatonin
More information about this product: Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland.
The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus) but outside the blood-brain barrier. The secretion of melatonin increases in darkness and decreases during exposure to light, thereby regulating the circadian rhythms of several biological functions, including the sleep-wake cycle. In particular, melatonin regulates the sleep-wake cycle by chemically causing drowsiness and lowering the body temperature. Melatonin is also implicated in the regulation of mood, learning and memory, immune activity, dreaming, fertility and reproduction. Melatonin is also an effective antioxidant. Most of the actions of melatonin are mediated through the binding and activation of melatonin receptors. Individuals with autism spectrum disorders (ASD) may have lower than normal levels of melatonin. A 2008 study found that unaffected parents of individuals with ASD also have lower melatonin levels, and that the deficits were associated with low activity of the ASMT gene, which encodes the last enzyme of melatonin synthesis. Reduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.
Melatonin is a type of Melatonin agonists
Melatonin agonists are a class of pharmaceutical active pharmaceutical ingredients (APIs) that interact with melatonin receptors in the body. Melatonin is a hormone naturally produced by the pineal gland in the brain and is involved in regulating the sleep-wake cycle.
Melatonin agonists mimic the effects of melatonin by binding to melatonin receptors in the brain. By activating these receptors, they help regulate circadian rhythms and promote sleep. These APIs are commonly used in the treatment of sleep disorders, such as insomnia and jet lag.
One widely used melatonin agonist is ramelteon, which selectively binds to melatonin receptors MT1 and MT2. It has a high affinity for these receptors, making it effective in promoting sleep without causing significant side effects.
Melatonin agonists offer several advantages over traditional sleep medications. They have a favorable safety profile, with minimal risk of dependence or abuse. Unlike sedative-hypnotic drugs, melatonin agonists do not suppress natural sleep architecture and are less likely to cause daytime drowsiness.
In addition to their sleep-promoting properties, melatonin agonists have shown potential in the treatment of other conditions. Research suggests they may be beneficial in managing circadian rhythm disorders, such as shift work disorder and delayed sleep phase syndrome.
Overall, melatonin agonists are a promising class of pharmaceutical APIs for improving sleep quality and addressing sleep-related disorders. Their unique mechanism of action and favorable safety profile make them a valuable option for individuals seeking effective and reliable sleep aids.
Melatonin manufacturers | traders | suppliers
We have 10 companies offering Melatonin produced in 5 different countries.
Get in contact with the supplier of your choice:
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Xi'an Tian Guangyuan Biotech Co.,Ltd from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- LGM Pharma from United States, product country of origin World
- Aurora Industry Co., Ltd from China, product country of origin China
- Duchefa Farma B.V. from Netherlands, product country of origin India
- Caesar & Loretz GmbH (CAELO) from Germany, product country of origin Unknown
- SETV Global from India, product country of origin India
- Flavine from Germany, product country of origin Unknown
- Flamma from Italy, product country of origin Italy
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