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Mevastatin | compare suppliers & send inquiries for free

Here you will find a list of producers, manufacturers and traders of Mevastatin. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
China Zhejiang Hisun Pharma
Type: Producer
Produced in: China
China
China Livzon Group
Type: Producer
Produced in: China
China
China Guangdong Blue Treasure Pharmaceuticals
Type: Producer
Produced in: China
China
China Chongqing Daxin
Type: Producer
Produced in: China
China

Looking for Mevastatin 73573-88-3?

API | Excipient name:
Mevastatin 
Synonyms:
Compactin  
Cas Number:
73573-88-3 
DrugBank number:
DB06693 
Unique Ingredient Identifier:
1UQM1K0W9X

About Mevastatin

What can you use it for? Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels.

Two years later, the research group isolated a compound structurally similar to hydroxymethylglutarate (HMG) that inhibited the incorporation of acetate. The compound was proposed to bind to the reductase enzyme and was named compactin. Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself. Mevastatin is a pro-drug that is activated by in vivo hydrolysis of the lactone ring. It has served as one of the lead compounds for the development of the synthetic compounds used today.

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Mevastatin manufacturers | traders | suppliers
We have 4 companies offering Mevastatin from 1 different countries.

Get in contact with the supplier of your choice:

  • Zhejiang Hisun Pharma from China
  • Livzon Group from China
  • Chongqing Daxin from China
  • Guangdong Blue Treasure Pharmaceuticals from China

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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