Mevastatin | compare suppliers & send inquiries for free
Zhejiang Hisun Pharma
Guangdong Blue Treasure Pharmaceuticals
Looking for Mevastatin 73573-88-3?
What can you use it for? Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels.
Two years later, the research group isolated a compound structurally similar to hydroxymethylglutarate (HMG) that inhibited the incorporation of acetate. The compound was proposed to bind to the reductase enzyme and was named compactin. Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself. Mevastatin is a pro-drug that is activated by in vivo hydrolysis of the lactone ring. It has served as one of the lead compounds for the development of the synthetic compounds used today.
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Mevastatin manufacturers | traders | suppliers
We have 4 companies offering Mevastatin from 1 different countries.
Get in contact with the supplier of your choice:
- Zhejiang Hisun Pharma from China
- Livzon Group from China
- Chongqing Daxin from China
- Guangdong Blue Treasure Pharmaceuticals from China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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