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Looking for Olmesartan 144689-24-7?
- API | Excipient name:
- Olmesartan
- Synonyms:
- Olmesartan medoxomil, 144689-63-4
- Cas Number:
- 144689-24-7
- DrugBank number:
- DB00275
- Unique Ingredient Identifier:
- 8W1IQP3U10
About Olmesartan
What makes Olmesartan unique? Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium. Olmesartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions.
Pharmacological blockade of RAAS via AT1 receptor blockade inhibits negative regulatory feedback within RAAS, which is a contributing factor to the pathogenesis and progression of cardiovascular disease, heart failure, and renal disease. In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.
You can find more info about this product by clicking on the DB ID above.
Olmesartan manufacturers | traders | suppliers
We have 59 companies offering Olmesartan from 7 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China
- Chemicea Pharmaceuticals Pvt Ltd from India
- Anlon Healthcare Pvt. Ltd. from India
- MSN Labs. from India
- TIEFENBACHER API + Ingredients from Germany
- JINLAN Pharm-Drugs Technology Co., Ltd. from China
- Lupin from India
- Sigmak Lifesciences from India
- Vasudha Pharma from India
- Morepen Laboratories Limited from India
- Synergene Active Ingredients Pvt Ltd from India
- Venkata Narayana Active Ingredients Private Limited from India
- CTX Lifesciences from India
- Maithili Life Sciences from India
- Nutra Specialities from India
- Zhejiang Tianyu from China
- Aurobindo from India
- Divis Labs. from India
- Mylan from India
- Dr. Reddy's from India
- Cadila Pharma from India
- Granules India from India
- Menovo from China
- Interquim from Spain
- R. L. Fine Chem from India
- Zhejiang Huahai Pharma from China
- Jubilant Generics from India
- Macleods Pharma from India
- Alembic Pharma from India
- Chinoin from Hungary
- Glenmark Pharma from India
- Amoli Organics from India
- Hetero Labs from India
- Dongbang FTL from South Korea
- Teva from Israel
- G.C. Chemie Pharmie Ltd from India
- Hikal from India
- Torrent Pharma from India
- Kolon Life Science from South Korea
- Unnati Pharmaceuticals Pvt Ltd from India
- Unichem Labs. from India
- Teva India from Israel
- HEC Pharm from Germany
- Glochem from India
- Qilu Tianhe from China
- Daiichi Sankyo from Japan
- Cadila Healthcare from India
- Cipla from India
- Zhuhai Rundu from China
- KRKA from Slovenia
- Verdant Life Sciences from India
- EstechPharma from South Korea
- Sumitomo Chemical from Japan
- Sintenovo from Spain
- Beijing Hope from China
- Humble Healthcaare from India
- Resolution Limited from China
- Huanggang Luban Pharmaceutical Co Ltd from China
- Hiral Labs from India
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