Olmesartan | compare suppliers & send inquiries for free
Looking for Olmesartan 144689-24-7?
- API | Excipient name:
- Olmesartan
- Synonyms:
- Olmesartan medoxomil, 144689-63-4
- Cas Number:
- 144689-24-7
- DrugBank number:
- DB00275
- Unique Ingredient Identifier:
- 8W1IQP3U10
About Olmesartan
What makes Olmesartan unique? Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium. Olmesartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions.
Pharmacological blockade of RAAS via AT1 receptor blockade inhibits negative regulatory feedback within RAAS, which is a contributing factor to the pathogenesis and progression of cardiovascular disease, heart failure, and renal disease. In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.
You can find more info about this product by clicking on the DB ID above.
Olmesartan manufacturers | traders | suppliers
We have 60 companies offering Olmesartan from 7 different countries.
Get in contact with the supplier of your choice:
- Acura Labs from India
- Shandong Octagon Chemicals Limited from China
- Sigmak Lifesciences from India
- Chemicea Pharmaceuticals Pvt Ltd from India
- Anlon Healthcare Pvt. Ltd. from India
- MSN Labs. from India
- TIEFENBACHER API + Ingredients from Germany
- JINLAN Pharm-Drugs Technology Co., Ltd. from China
- Lupin from India
- Morepen Laboratories Limited from India
- Synergene Active Ingredients Pvt Ltd from India
- Venkata Narayana Active Ingredients Private Limited from India
- CTX Lifesciences from India
- Maithili Life Sciences from India
- Nutra Specialities from India
- Zhejiang Tianyu from China
- Aurobindo from India
- Micro Labs from India
- Divis Labs. from India
- Mylan from India
- Dr. Reddy's from India
- Menovo from China
- Granules India from India
- Interquim from Spain
- Cadila Pharma from India
- Moehs from Spain
- R. L. Fine Chem from India
- Jubilant Generics from India
- Zhejiang Huahai Pharma from China
- Macleods Pharma from India
- Chinoin from Hungary
- Amoli Organics from India
- Alembic Pharma from India
- Glenmark Pharma from India
- Hetero Labs from India
- Teva API from Israel
- Dongbang FTL from South Korea
- G.C. Chemie Pharmie Ltd from India
- Hikal from India
- Kolon Life Science from South Korea
- Torrent Pharma from India
- Unnati Pharmaceuticals Pvt Ltd from India
- Unichem Labs. from India
- Teva API India from Israel
- Qilu Tianhe from China
- Glochem from India
- HEC Pharm from Germany
- Cadila Healthcare from India
- Daiichi Sankyo from Japan
- Zhuhai Rundu from China
- Cipla from India
- KRKA from Slovenia
- Sumitomo Chemical from Japan
- Verdant Life Sciences from India
- Sintenovo from Spain
- Humble Healthcaare from India
- Huanggang Luban Pharmaceutical Co Ltd from China
- Beijing Hope from China
- Resolution Limited from China
- Hiral Labs from India
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