Pioglitazone | compare suppliers & send inquiries for free
Looking for Pioglitazone 111025-46-8?
Some technical information about this product: Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class of medications, which also includes rosiglitazone and troglitazone, exerts its pharmacological effect primarily by promoting insulin sensitivity and the improved uptake of blood glucose4 via agonism at the peroxisome proliferator-activated receptor-gamma (PPARγ). PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. Thiazolidinediones, including pioglitazone, have fallen out of favor in recent years due to the presence of multiple adverse effects and warnings regarding their use (e.
g. congestive heart failure, bladder cancer) and the availability of safer and more effective alternatives for patients with type 2 diabetes mellitus.
Check who is selling Pioglitazone in the overview above.
Pioglitazone manufacturers | traders | suppliers
We have 30 companies offering Pioglitazone from 7 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China
- Hetero Drugs from India
- Lupin from India
- Ind-Swift Labs. from India
- Aarti Drugs from India
- International Drug & Chemical co. from India
- Erregierre from Italy
- Aurobindo from India
- Biocon from India
- Dr. Reddy's from India
- Mylan from India
- Cadila Pharma from India
- Zhejiang Hisun Pharma from China
- Hetero Labs from India
- Macleods Pharma from India
- JPN Pharma from India
- Zhejiang Huahai Pharma from China
- Teva API from Israel
- Inist St Co. from South Korea
- USV from India
- MSN Organics from India
- Cadila Healthcare from India
- Teva API India from Israel
- Zhejiang Huayi from China
- Signa from Mexico
- Wockhardt from India
- Sumitomo Chemical from Japan
- Cipla from India
- Aarambh Life Science from India
- Hanmi Fine Chemical from South Korea
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