Simvastatin API Manufacturers & Suppliers

Looking for Simvastatin API 79902-63-9?

Description:

Here you will find a list of producers, manufacturers and distributors of Simvastatin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Simvastatin 

Synonyms:

MK-733 , Simvastatin , Simvastatina , Simvastatine , Simvastatinum , Synvinolin , Zocor  

Cas Number:

79902-63-9 

DrugBank number:

DB00641 

Unique Ingredient Identifier:

AGG2FN16EV

Simvastatin is a type of Lipid-lowering agents

Lipid-lowering agents are a category of pharmaceutical active ingredients (APIs) that are widely used in the treatment of hyperlipidemia, a condition characterized by elevated levels of lipids (such as cholesterol and triglycerides) in the blood. These agents play a crucial role in managing lipid abnormalities and reducing the risk of cardiovascular diseases.

One of the most commonly prescribed lipid-lowering agents is statins. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. By blocking this enzyme, statins effectively lower cholesterol levels in the bloodstream.

Another class of lipid-lowering agents is fibric acid derivatives, which primarily target triglyceride levels. These agents activate a nuclear receptor known as PPAR-alpha, which regulates lipid metabolism. By activating PPAR-alpha, fibric acid derivatives enhance the breakdown of triglycerides and increase the elimination of fatty acids from the bloodstream.

Additionally, bile acid sequestrants are often used as lipid-lowering agents. These agents bind to bile acids in the intestine, preventing their reabsorption. As a result, the liver utilizes more cholesterol to produce new bile acids, leading to a decrease in circulating cholesterol levels.

Lipid-lowering agents are available in various formulations, including tablets, capsules, and suspensions, allowing for convenient administration. They are usually prescribed alongside lifestyle modifications, such as dietary changes and regular exercise, to optimize the management of hyperlipidemia.

It is important to note that the use of lipid-lowering agents should be under the supervision of a healthcare professional, as they may have potential side effects and interactions with other medications. Proper monitoring of lipid levels and regular follow-up visits are essential for ensuring the effectiveness and safety of these pharmaceutical agents.

• AMARI TRADE ALLIANEC LLP from India, product country of origin IndiaChina
• Rochem International, Inc. from United States, product country of origin United States
• LGM Pharma from United States, product country of origin World
• Aurora Industry Co., Ltd from China, product country of origin China
• Shandong Octagon Chemicals Limited from China, product country of origin China
• Shangyu Jingxin from China, product country of origin China
• Southwest Synthetic Pharmaceutical Corp. from China, product country of origin China
• Aquatic Remedies Pvt Ltd from India, product country of origin India
• Zhejiang Hisun Pharma from China, product country of origin China
• UK Chemipharm from South Korea, product country of origin South Korea
• KRKA from Slovenia, product country of origin Unknown
• TAPI from Israel, product country of origin Israel
• Krebs Biochem from India, product country of origin India
• Biocon from India, product country of origin India
• Kolon Life Science from South Korea, product country of origin South Korea
• Zhejiang Jiangbei from China, product country of origin China
• Sterling Biotech from India, product country of origin India
• Osaka Synthetic Chemical Lab from Japan, product country of origin Japan
• Zhejiang Jingxin Pharma from China, product country of origin China
• Themis Medicare from India, product country of origin India
• Sun Pharma from India, product country of origin India
• Hetero Labs from India, product country of origin Unknown
• Divis Labs. from India, product country of origin India
• Shaoxing Hantai Pharma from China, product country of origin China
• Mylan from India, product country of origin India
• Lupin from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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