Sodium bicarbonate API API Manufacturers & Suppliers

Looking for Sodium bicarbonate API API 144-55-8?

Description:

Here you will find a list of producers, manufacturers and distributors of Sodium bicarbonate API. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Sodium bicarbonate API 

Synonyms:

Baking soda , Bicarbonate of soda , Carbonic acid monosodium salt , E500 , Natriumhydrogenkarbonat , Sodium acid carbonate , Sodium bicarbonate , Sodium hydrogen carbonate , Sodium hydrogencarbonate , Sodium hydrogen carbonate , BICAR® Pharma API , Sodium bicarbonate  

Cas Number:

144-55-8 

DrugBank number:

DB01390 

Unique Ingredient Identifier:

8MDF5V39QO

Sodium bicarbonate API is a type of Alkalinizing agents

Alkalinizing agents, a pharmaceutical API category, refers to a group of substances used to increase the pH (alkalinity) of a solution or body fluid. These agents play a crucial role in various medical applications, such as the treatment of acidosis, kidney disorders, and certain drug overdoses.

One commonly used alkalinizing agent is sodium bicarbonate, which is highly effective in raising the pH of blood and urine. It works by neutralizing excess acid and restoring the acid-base balance in the body. Sodium bicarbonate is often administered intravenously in emergency situations to rapidly correct severe acidosis.

Another alkalinizing agent, acetazolamide, is frequently employed in the treatment of glaucoma and certain types of epilepsy. By inhibiting carbonic anhydrase, acetazolamide reduces the production of bicarbonate ions, leading to a systemic decrease in pH. This mechanism is particularly useful in lowering the intraocular pressure associated with glaucoma.

Alkalinizing agents are also utilized in the management of certain drug toxicities. For instance, methotrexate, a chemotherapy medication, can cause severe toxicity if its elimination is hindered. Alkalinizing the urine with agents like sodium bicarbonate enhances methotrexate solubility, preventing the formation of toxic crystals in the kidneys.

In conclusion, alkalinizing agents are indispensable pharmaceutical APIs that help correct acid-base imbalances, treat specific medical conditions, and mitigate drug toxicities. Their diverse applications make them valuable tools in modern medicine.

• Pharm Rx Chemical Corp from United States, product country of origin Unknown
• Fujifilm Wako Pure Chemical Corporation from Japan, product country of origin Japan
• Caesar & Loretz GmbH (CAELO) from Germany, product country of origin Unknown
• Duchefa Farma B.V. from Netherlands, product country of origin Unknown
• Hänseler AG from Switzerland, product country of origin Switzerland
• Global Pharma Tek from India, product country of origin India
• Emmennar Pharma from India, product country of origin India
• ACS Dobfar from Italy, product country of origin Italy
• Solvay Operations from France, product country of origin France
• Solvay Quimica from Spain, product country of origin Spain

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