Country of origin

    Tolbutamide | compare suppliers & send inquiries for free

    Here you will find a list of producers, manufacturers and traders of Tolbutamide. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
    China Zhejiang Changming
    Type: Producer
    Produced in: China
    Germany TIEFENBACHER API + Ingredients
    Type: Distributor
    Produced in: Germany
    India Kothari Phyto
    Type: Producer
    Produced in: India
    India Quantum Drugs & Chemicals
    Type: Producer
    Produced in: India
    Italy Dipharma Francis S.r.l.
    Type: Producer
    Produced in: Italy

    Looking for Tolbutamide 64-77-7?

    API | Excipient name:
    Orinase, Tolbutamida, Tolbutamide, Tolbutamidum, Tolylsulfonylbutylurea  
    Cas Number:
    DrugBank number:
    Unique Ingredient Identifier:

    About Tolbutamide

    Do you want to know more about Tolbutamide? You can find a small explanation about it here. Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release.

    Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Tolbutamide appears to be metabolized in the liver. Tolbutamide and its metabolites are excreted in urine (75-85%) and feces.

    Check who is selling Tolbutamide in the overview above.

    Tolbutamide manufacturers | traders | suppliers
    We have 5 companies offering Tolbutamide from 4 different countries.

    Get in contact with the supplier of your choice:

    • TIEFENBACHER API + Ingredients from Germany
    • Zhejiang Changming from China
    • Dipharma Francis S.r.l. from Italy
    • Quantum Drugs & Chemicals from India
    • Kothari Phyto from India

    Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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