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Amfebutamone (Bupropion)
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Established in: 2021
MOQ: -
Employees: 19
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Looking for Bupropion API 34911-55-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Bupropion. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Bupropion
- Synonyms:
- Amfebutamone
- Cas Number:
- 34911-55-2
- DrugBank number:
- DB01156
- Unique Ingredient Identifier:
- 01ZG3TPX31
About Bupropion
You can find a short description about Bupropion here. Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake of the neurotransmitters norepinephrine and dopamine from the synaptic cleft, therefore prolonging their duration of action within the neuronal synapse and the downstream effects of these neurotransmitters. More specifically, bupropion binds to the norepinephrine transporter (NET) and the dopamine transporter (DAT) Bupropion was originally classified as an "atypical" antidepressant because it does not exert the same effects as the classical antidepressants such as Monoamine Oxidase Inhibitors (MAOIs), Tricyclic Antidepressants (TCAs), or Selective Serotonin Reuptake Inhibitors (SSRIs).
While it has comparable effectiveness to typical first-line options for the treatment of depression such as SSRIs.
Check who is selling Bupropion in the overview above.
Bupropion is a type of Antidepressants
Antidepressants are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of depression and other mood disorders. These medications work by balancing the levels of certain chemicals in the brain called neurotransmitters, such as serotonin, norepinephrine, and dopamine.
There are several types of antidepressants available, each with its own mechanism of action and efficacy. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed as a first-line treatment for depression. They prevent the reabsorption of serotonin, resulting in increased serotonin levels in the brain. Examples of popular SSRIs include fluoxetine, sertraline, and escitalopram.
Tricyclic antidepressants (TCAs) are another class of antidepressants that work by blocking the reuptake of both serotonin and norepinephrine. They are generally used when SSRIs are ineffective or not well-tolerated. Amitriptyline, nortriptyline, and imipramine are commonly prescribed TCAs.
Other antidepressants include serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants, and monoamine oxidase inhibitors (MAOIs). SNRIs, such as venlafaxine and duloxetine, inhibit the reuptake of both serotonin and norepinephrine. Atypical antidepressants, including bupropion and mirtazapine, have diverse mechanisms of action, targeting multiple neurotransmitters. MAOIs, such as phenelzine and tranylcypromine, work by inhibiting the enzyme monoamine oxidase, which breaks down neurotransmitters.
It is important to note that antidepressants may have various side effects and require close monitoring by healthcare professionals. Dosages and treatment duration vary based on individual needs and response. Antidepressants are typically prescribed as part of a comprehensive treatment plan that may include psychotherapy and lifestyle modifications.
In conclusion, antidepressants are a vital category of pharmaceutical APIs used to manage depression and related mood disorders. They act on neurotransmitters in the brain to alleviate symptoms and improve overall well-being. It is crucial to consult with a healthcare provider to determine the most suitable antidepressant and monitor its effects.
Bupropion manufacturers | traders | suppliers
We have 11 companies offering Bupropion produced in 3 different countries.
Get in contact with the supplier of your choice:
- SETV Global from India, product country of origin India
- Chemi S.p.A. from Italy, product country of origin Italy
- Zhejiang Supor from China, product country of origin China
- Sai-Tech Pharmaceuticals Pvt. Ltd. from India, product country of origin India
- Zhejiang Apeloa Tospo-Jiayuan from China, product country of origin China
- Mahalaxmi Chemi Pharm from India, product country of origin India
- Hikal from India, product country of origin India
- Divis Labs. from India, product country of origin India
- Erregierre from Italy, product country of origin Italy
- Hetero Drugs from India, product country of origin India
- Sun Pharma from India, product country of origin India
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