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Located in:

India

Produced in:

India

Established in: 1989

MOQ: -

Employees: 5000+

6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO

R&D Centers with capabilities of ANDAs, DMFs and NDDS

462+ patents filed for drug substances and polymorphs

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Produced in:

Switzerland

Established in: 1968

MOQ: 1 kg

Employees: 50+

Warehouse stock of nearly all APIs

GMP, GDP and ISO certified

Customisable (small-sized) packages

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World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

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China

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Located in:

India

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India

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Japan

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Japan

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Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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Located in:

India

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India

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Germany

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Spain

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Looking for Nifedipine API 21829-25-4?

Description:
Here you will find a list of producers, manufacturers and distributors of Nifedipine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Nifedipine 
Synonyms:
Adalat , Adapine , Coracten , Nifecard , Nifecor , Nifedipine , Nifedipino , Nifedipinum , Nifedipres , Procardia  
Cas Number:
21829-25-4 
DrugBank number:
DB01115 
Unique Ingredient Identifier:
I9ZF7L6G2L

About Nifedipine

Some technical information about this product: Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972 Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer durations of action. The most popular of the third generation dihydropyridines is amlodipine. Nifedipine was granted FDA approval on 31 December 1981.

Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.

Nifedipine is a type of Calcium Channel Blockers


Calcium channel blockers (CCBs) are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the treatment of various cardiovascular conditions. CCBs work by blocking the influx of calcium ions into smooth muscle cells and cardiac muscle cells, leading to vasodilation and reduced cardiac contractility.

CCBs are commonly prescribed to manage hypertension (high blood pressure), angina (chest pain), and certain arrhythmias (irregular heart rhythms). They are also effective in treating Raynaud's disease and migraine headaches. These medications exert their therapeutic effects by selectively inhibiting L-type calcium channels in the heart and blood vessels.

By blocking calcium channels, CCBs help relax and widen blood vessels, reducing peripheral resistance and improving blood flow. This mechanism of action lowers blood pressure, relieves angina symptoms, and helps prevent certain types of abnormal heart rhythms.

Some well-known CCBs include amlodipine, nifedipine, diltiazem, and verapamil. These medications are available in various formulations, including immediate-release and extended-release tablets, as well as injectable solutions.

It's important to note that CCBs may cause certain side effects, such as dizziness, headache, flushing, and ankle swelling. They may also interact with other medications, so it's crucial to consult a healthcare professional before starting or changing any CCB therapy.

In summary, Calcium channel blockers are a subcategory of cardiovascular medications that inhibit calcium channels, resulting in vasodilation, decreased cardiac contractility, and overall therapeutic effects in conditions such as hypertension, angina, and arrhythmias. Proper medical supervision and individualized treatment plans are essential for optimizing the use of CCBs.


Nifedipine (Calcium Channel Blockers), classified under Antihypertensive agents


Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.



Nifedipine manufacturers | traders | suppliers

We have 15 companies offering Nifedipine produced in 9 different countries.

Get in contact with the supplier of your choice:

  • Shilpa Medicare Ltd from India, product country of origin India
  • Duchefa Farma B.V. from Netherlands, product country of origin Switzerland
  • LGM Pharma from United States, product country of origin World
  • Chifeng Arker Tech. from China, product country of origin China
  • Unique Chemicals from India, product country of origin India
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Mikuni Pharmaceutical Industry from Japan, product country of origin Japan
  • Teva API from Israel, product country of origin Unknown
  • Sharon Bio-Medicine from India, product country of origin India
  • Bayer from Germany, product country of origin Unknown
  • Moehs from Spain, product country of origin Spain
  • Ipca Labs. from India, product country of origin India
  • Siegfried from Germany, product country of origin Unknown
  • Evonik TC from Germany, product country of origin Germany
  • Sicor from Italy, product country of origin Italy

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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