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Donepezilum (Donepezil) API Manufacturers & Suppliers

Looking for Donepezil API 120014-06-4?

Description:

Here you will find a list of producers, manufacturers and distributors of Donepezil. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Donepezil 

Synonyms:

Domepezil , Donepezil , Donepezil , Donepezilo , Donepezilum  

Cas Number:

120014-06-4 

DrugBank number:

DB00843 

Unique Ingredient Identifier:

8SSC91326P

Donepezil is a type of Cholinesterase inhibitors

Cholinesterase inhibitors are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a crucial role in the treatment of various medical conditions. These compounds work by inhibiting the activity of the enzyme cholinesterase, which breaks down the neurotransmitter acetylcholine in the body.

Acetylcholine is involved in many important processes in the central and peripheral nervous systems, including muscle contractions, memory, and cognitive functions. By inhibiting cholinesterase, these APIs help to increase the levels of acetylcholine in the brain and enhance cholinergic neurotransmission.

Cholinesterase inhibitors have proven to be highly effective in the management of Alzheimer's disease, a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. These APIs, such as donepezil, rivastigmine, and galantamine, are commonly used as symptomatic treatments to alleviate cognitive impairment and enhance patients' overall quality of life.

Furthermore, cholinesterase inhibitors find applications beyond Alzheimer's disease. They are also utilized in the treatment of other conditions, including Parkinson's disease, glaucoma, myasthenia gravis, and certain types of dementia.

The development and utilization of cholinesterase inhibitors have revolutionized the treatment options for patients suffering from these debilitating disorders. As research in neuroscience and pharmacology advances, the continuous refinement of cholinesterase inhibitors and the discovery of novel compounds within this subcategory hold promise for future therapeutic breakthroughs.

Donepezil (Cholinesterase inhibitors), classified under Central Nervous System Agents

Central Nervous System (CNS) Agents are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that specifically target the central nervous system. The CNS encompasses the brain and spinal cord, playing a vital role in regulating and controlling various bodily functions, including cognition, movement, emotions, and sensory perception. These agents are designed to interact with specific receptors, enzymes, or ion channels within the CNS to modulate neural activity and restore normal functioning.

CNS agents comprise a diverse range of pharmaceutical APIs, including analgesics, anesthetics, antipsychotics, sedatives, hypnotics, anti-epileptics, and antidepressants. Each subcategory addresses distinct neurological disorders and conditions. For instance, analgesics alleviate pain by targeting receptors in the brain and spinal cord, while antipsychotics are employed to manage psychosis symptoms in mental illnesses such as schizophrenia.

The development of CNS agents involves rigorous research, molecular modeling, and extensive clinical trials to ensure safety, efficacy, and specific target engagement. Pharmaceutical companies invest significant resources in identifying novel drug targets, synthesizing new compounds, and optimizing their pharmacological properties. These agents undergo rigorous regulatory evaluations and must adhere to stringent quality standards and guidelines.

Given the prevalence of CNS disorders globally, the market demand for effective CNS agents is substantial. The development of innovative CNS APIs not only improves patient outcomes but also provides valuable commercial opportunities for pharmaceutical companies. Continued advancements in CNS agent research and development hold the promise of groundbreaking therapies that can improve the quality of life for individuals affected by neurological conditions.

• Shandong Chenghui Shuangda Pharmaceutical Co. Ltd. from China, product country of origin China
• Xi'an ZB Biotech Co., Ltd from China, product country of origin China
• Shandong Octagon Chemicals Limited from China, product country of origin China
• Sinoway industrial Co.,Ltd from China, product country of origin China
• LGM Pharma from United States, product country of origin World
• Gonane Pharma from India, product country of origin India
• Torrent Pharma from India, product country of origin India
• Vasudha Pharma Chem Ltd. from India, product country of origin India
• TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
• Kolon Life Science from South Korea, product country of origin South Korea
• Zhejiang East Asia Pharmaceutical from China, product country of origin China
• Sichuan Benepure from China, product country of origin China
• Finetech Pharma from Israel, product country of origin Israel
• Zhejiang Hisun Pharma from China, product country of origin China
• Teva API from Israel, product country of origin Unknown
• Hikal from India, product country of origin India
• Zhejiang East-Asia Pharma from China, product country of origin China
• Unnati Pharmaceuticals Pvt Ltd from India, product country of origin India
• USV from India, product country of origin India
• Chongqing Zein from China, product country of origin China
• PLIVA from Czech Republic, product country of origin Czech Republic
• Dr. Reddy's from India, product country of origin India
• Ind-Swift Labs. from India, product country of origin India
• Unichem Labs. from India, product country of origin India
• Piramal Healthcare from United Kingdom, product country of origin India
• Hetero Drugs from India, product country of origin India
• Sun Pharma from India, product country of origin India
• Piramal Pharma Solutions from India, product country of origin India
• Lupin from India, product country of origin India
• Cipla from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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