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Xiliarx (Vildagliptin) API Manufacturers

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HIGHLIGHTED

Located in:

India

Produced in:

India

Established in: 1978

MOQ: -

Employees: 10k+

199 API-Related Granted Patents

Global Presence in 50+ Markets

Advanced technology and R&D Capabilities

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • USDMF

  • GMP

  • CoA

  • ISO9001

  • MSDS

  • BSE/TSE

HIGHLIGHTED

Located in:

Latvia

Producer

Produced in:

Latvia

Established in: 1972

MOQ: -

Employees: 1,000+

EU-GMP for APIs and CEP for certain APIs

Exporting to over 50 countries worldwide

Long-standing technological advantage in adamantane, quinuclidine and nitrofurane chemistry

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • EDMF/ASMF

  • BSE/TSE

  • coa

  • USDMF

  • MSDS

  • GMP

  • ISO

Distributor

Produced in:

World

Established in: 1997

MOQ: -

Employees: 50

GMP and GDP certified

Biotechnological research leadership and manufacturer

Extensive distribution network for product global accessibility

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • USDMF

  • CEP

  • JDMF

  • KDMF

  • GMP

  • CoA

  • MSDS

  • ISO9001

Produced in:

China

Established in: 1987

MOQ: 100 g

Employees: 50+

ISO 9001:2015 & SGS audited supplier

One-stop CDMO Solutions for APl and Key intermediates

Specialized in APIs & Pharmaceutical Intermediates for 37 years

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • CoA

  • ISO9001

  • MSDS

  • GMP

  • USDMF

Produced in:

China

Established in: 2011

MOQ: 100 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • CoA

  • BSE/TSE

  • MSDS

  • ISO9001

Producer

Produced in:

India

Established in: 2021

MOQ: -

Employees: 19

API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides

Small quantity APIs to commercial scale

GMP and USFDA certification based on quantity, order, assignment.

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • CoA

  • FDA

Located in:

China

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • USDMF

  • CoA

Located in:

China

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • coa

Producer

Produced in:

India

Established in: 1995

MOQ: -

Employees: 10000

Fermentation technology Experts

Partnerships with 1200 pharma companies in 100+ countries

US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • CoA

Located in:

Italy

Producer

Produced in:

United States

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • CoA

Located in:

Hungary

Produced in:

Hungary

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • CoA

Located in:

Slovenia

Producer

Produced in:

Slovenia

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • CoA

Contact supplier

Replies slower than most

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • CoA

Located in:

China

Producer

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • CoA

  • FDA

  • GMP

  • EDMF/ASMF

Contact supplier

Replies slower than most

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • WC

  • CoA

  • GMP

  • JDMF

Located in:

China

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • USDMF

  • CoA

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • USDMF

  • CoA

Contact supplier

Replies slower than most

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • WC

  • CoA

  • USDMF

Located in:

Spain

Producer

Produced in:

Malta

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • CoA

  • GMP

Located in:

Spain

Producer

Produced in:

Spain

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • USDMF

  • + 0

All certificates

  • GMP

  • CoA

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Looking for Vildagliptin API 274901-16-5?

Description:
Here you will find a list of producers, manufacturers and distributors of Vildagliptin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Vildagliptin 
Synonyms:
Galvus , EQUA , Jalra , LAF 237 , Vildagliptin , Xiliarx  
Cas Number:
274901-16-5 
DrugBank number:
DB04876 
Unique Ingredient Identifier:
I6B4B2U96P

About Vildagliptin

Here you will find more information about Vildagliptin. Vildagliptin, previously identified as LAF237, is a new oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vidagliptin subsequently acts by inhibiting the inactivation of glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) by DPP-4. This inhibitory activity ultimately results in a two-fold action where GLP-1 and GIP are present to potentiate the secretion of insulin by beta cells and suppress glucagon secretion by alpha cells in the islets of Langerhans in the pancreas.

It is currently in clinical trials in the USA and has been shown to reduce hyperglycemia in type 2 diabetes mellitus. While the drug is still not approved for use in the US, it was approved in Feb 2008 by European Medicines Agency for use within the EU and is listed on the Australian PBS with certain restrictions.

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Vildagliptin is a type of DPP4-Inhibitors


DPP4-Inhibitors, or dipeptidyl peptidase-4 inhibitors, belong to the subcategory of pharmaceutical active ingredients known for their therapeutic role in managing type 2 diabetes mellitus. These inhibitors work by targeting and inhibiting the action of the enzyme dipeptidyl peptidase-4 (DPP4) in the body.

DPP4 is responsible for breaking down incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By inhibiting DPP4, DPP4-Inhibitors enhance the levels and activity of these hormones. GLP-1 and GIP play crucial roles in regulating blood sugar levels by stimulating insulin release, inhibiting glucagon secretion, and slowing down gastric emptying.

The main advantage of DPP4-Inhibitors is their ability to improve glycemic control without the risk of hypoglycemia, which is a common side effect of some other diabetes medications. They are typically used as an adjunct therapy in combination with other antidiabetic agents, such as metformin, to achieve optimal glucose management.

Commonly prescribed DPP4-Inhibitors include sitagliptin, saxagliptin, linagliptin, and alogliptin. These drugs are available in oral tablet formulations, allowing for convenient administration. They have shown efficacy in lowering HbA1c levels and have a favorable safety profile.

It is important to note that DPP4-Inhibitors are not suitable for individuals with type 1 diabetes or those with a history of pancreatitis. As with any medication, there may be potential side effects, such as upper respiratory tract infections, headache, and gastrointestinal discomfort, which should be discussed with a healthcare professional.

In conclusion, DPP4-Inhibitors are a subcategory of pharmaceutical APIs that act by inhibiting the enzyme DPP4, thereby enhancing the effects of incretin hormones involved in glucose regulation. They are widely used in the management of type 2 diabetes mellitus, offering glycemic control benefits with a reduced risk of hypoglycemia.


Vildagliptin (DPP4-Inhibitors), classified under Anti-diabetics


Anti-diabetics, belonging to the pharmaceutical API (Active Pharmaceutical Ingredient) category, are a group of compounds designed to manage and treat diabetes mellitus, a chronic metabolic disorder characterized by high blood sugar levels. These medications play a vital role in controlling diabetes and preventing complications associated with the disease.

Anti-diabetics encompass a wide range of drug classes, including biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists. Each class works through different mechanisms to regulate blood sugar levels and improve insulin sensitivity.

Biguanides, such as metformin, reduce glucose production by the liver and enhance insulin sensitivity in peripheral tissues. Sulfonylureas, like glipizide, stimulate insulin secretion from pancreatic beta cells. Thiazolidinediones, including pioglitazone, improve insulin sensitivity in muscle and adipose tissues. DPP-4 inhibitors, such as sitagliptin, increase insulin release and inhibit glucagon secretion. SGLT2 inhibitors, like dapagliflozin, decrease renal glucose reabsorption, leading to increased urinary glucose excretion. GLP-1 receptor agonists, such as exenatide, enhance insulin secretion, suppress glucagon release, slow gastric emptying, and promote satiety.

These anti-diabetic APIs serve as the foundational ingredients for the formulation of various oral tablets, capsules, and injectable medications used in the treatment of diabetes. By targeting different aspects of glucose regulation, they help patients achieve and maintain optimal blood sugar levels, thus reducing the risk of diabetic complications, such as cardiovascular disease, neuropathy, and nephropathy.

It is crucial for healthcare professionals to prescribe and administer these anti-diabetic medications appropriately, considering factors like the patient's medical history, co-existing conditions, and potential drug interactions. Regular monitoring of blood glucose levels and close medical supervision are necessary to ensure effective diabetes management.

In conclusion, anti-diabetics form a critical category of pharmaceutical APIs used for the treatment of diabetes. These compounds, encompassing various drug classes, work through distinct mechanisms to regulate blood sugar levels and improve insulin sensitivity. By facilitating glucose control, anti-diabetic APIs help mitigate the risk of complications associated with diabetes mellitus, ultimately promoting better health outcomes for patients.



Vildagliptin manufacturers | traders | suppliers

We have 20 companies offering Vildagliptin produced in 9 different countries.

Get in contact with the supplier of your choice:

  • Jubilant Pharmova from India, product country of origin India
  • Olpha from Latvia, product country of origin Latvia
  • AXXO GmbH from Germany, product country of origin World
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • SETV Global from India, product country of origin India
  • Beijing Huikang Boyuan from China, product country of origin China
  • Tianjin Minxiang from China, product country of origin China
  • Biocon from India, product country of origin India
  • Cambrex from Italy, product country of origin United States
  • Gedeon Richter from Hungary, product country of origin Hungary
  • KRKA from Slovenia, product country of origin Slovenia
  • Lee Pharma from India, product country of origin India
  • Menovo from China, product country of origin China
  • Honour Lab from India, product country of origin India
  • Fuxing Long Rui Pharma from China, product country of origin China
  • Hikal from India, product country of origin India
  • MSN Pharma from India, product country of origin India
  • Medichem from Spain, product country of origin Malta
  • Moehs from Spain, product country of origin Spain

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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