Edoxaban
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Established in: 1984
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Looking for Edoxaban 480449-70-5?
- Description:
- Here you will find a list of producers, manufacturers and traders of Edoxaban. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Edoxaban
- Synonyms:
- Edoxaban Tosylate
- Cas Number:
- 480449-70-5
- DrugBank number:
- DB09075
- Unique Ingredient Identifier:
- NDU3J18APO
About Edoxaban
So, what does it do? Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) following 5-10 days of initial therapy with a parenteral anticoagulant. Traditionally, warfarin, a vitamin K antagonist, was used for stroke prevention in these individuals but effective use of this drug is limited by it's delayed onset, narrow therapeutic window, need for regular monitoring and INR testing, and numerous drug-drug and drug-food interactions.
This has prompted enthusiasm for newer agents such as dabigatran, apixaban, and rivaroxaban for effective clot prevention. In addition to once daily dosing, the benefits over warfarin also include significant reductions in hemorrhagic stroke and GI bleeding, and improved compliance, which is beneficial as many patients will be on lifelong therapy.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Edoxaban manufacturers | traders | suppliers
We have 6 companies offering Edoxaban from 2 different countries.
Get in contact with the supplier of your choice:
- Morepen Laboratories Ltd. from India
- Shandong Octagon Chemicals Limited from China
- Zhejiang Supor from China
- Cadila Healthcare from India
- Honour Lab from India
- MSN Life Sciences from India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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