Esomeprazole
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Produced in:
Established in: 1994
MOQ: -
Employees: 4,000
All our 5 plants are top notch and FDA approved
We are a backwards integrated company
We have received 24 CEP’s and 27 USDMF’s
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Looking for Esomeprazole 119141-88-7?
- Description:
- Here you will find a list of producers, manufacturers and traders of Esomeprazole. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Esomeprazole
- Synonyms:
- Esomeprazol , Esomeprazolum , Omeprazole S-form , Perprazole , Esomeprazole magnesium dihydrate
- Cas Number:
- 119141-88-7
- DrugBank number:
- DB00736
- Unique Ingredient Identifier:
- N3PA6559FT
About Esomeprazole
Some technical information about this product: Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be found in quadruple regimens for the treatment of H. pylori infections along with other antibiotics including Amoxicillin, Clarithromycin, and Metronidazole, for example Its efficacy is considered similar to other medications within the PPI class including Omeprazole, Pantoprazole, Lansoprazole, Dexlansoprazole, and Rabeprazole. Esomeprazole is the s-isomer of Omeprazole, which is a racemate of the S- and R-enantiomer.
Esomeprazole has been shown to inhibit acid secretion to a similar extent as Omeprazole, without any significant differences between the two compounds in vitro. Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme at the secretory surface of gastric parietal cells. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus. As the binding of esomeprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, esomeprazole's duration of antisecretory effect persists longer than 24 hours.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Esomeprazole manufacturers | traders | suppliers
We have 34 companies offering Esomeprazole from 5 different countries.
Get in contact with the supplier of your choice:
- Vasudha Pharma Chem Ltd. from India
- Jubilant Generics from India
- Jiangsu Zhongbang from China
- Zhejiang Yongtai Pharma from China
- Lee Pharma from India
- Zhejiang Changming from China
- Lupin from India
- Rajasthan Antibiotics from India
- Alkem Labs. from India
- Ehfield Co.,Ltd from China
- Mac Chem Products from India
- KRKA from Slovenia
- PCAS from France
- Shouguang Fukang from China
- HEC Pharm from Germany
- Cadila Healthcare from India
- Srini Pharma from India
- Sterile India from India
- Sandoz from Austria
- Torrent Pharma from India
- Menovo from China
- Zhejiang Huayi from China
- Fabbrica Italiana Sintetici (FIS) from Italy
- Zhejiang Neo-Dankong from China
- Cipla from India
- Hetero Drugs from India
- MSN Life Sciences from India
- Mylan from India
- Emcure Pharma from India
- Glenmark Pharma from India
- Dr. Reddy's from India
- Aurobindo from India
- Zhejiang Jinhua Conba from China
- Sun Pharma from India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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