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Simvastatine (Simvastatin)
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Distributor
Produced in:
Established in: 1994
MOQ: -
Employees: 50+
26+ years of distribution expertise with regulatory excellence
16 worldwide locations supplying high quality ingredients
All our manufacturer partners are cGMP complaint
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Produced in:
Established in: 2011
MOQ: 100 g
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Produced in:
Established in: 2005
MOQ: -
Employees: 200+
Portfolio of over 2,000 APIs
Precise quality control
End-to-end global regulatory support
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Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Producer
Produced in:
Established in: 1995
MOQ: -
Employees: 10000
Fermentation technology Experts
Partnerships with 1200 pharma companies in 100+ countries
US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations
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Looking for Simvastatin API 79902-63-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Simvastatin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Simvastatin
- Synonyms:
- MK-733 , Simvastatin , Simvastatina , Simvastatine , Simvastatinum , Synvinolin , Zocor
- Cas Number:
- 79902-63-9
- DrugBank number:
- DB00641
- Unique Ingredient Identifier:
- AGG2FN16EV
About Simvastatin
Do you want to know more about Simvastatin? You can find a small explanation about it here. Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase which catalyzes the conversion of HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as bad cholesterol), and very low-density lipoprotein (VLDL).
Prescribing of statin medications is considered standard practice following any cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes.
Ask the supplier for a certificate of analysis to find out more about the quality of Simvastatin.
Simvastatin is a type of Lipid-lowering agents
Lipid-lowering agents are a category of pharmaceutical active ingredients (APIs) that are widely used in the treatment of hyperlipidemia, a condition characterized by elevated levels of lipids (such as cholesterol and triglycerides) in the blood. These agents play a crucial role in managing lipid abnormalities and reducing the risk of cardiovascular diseases.
One of the most commonly prescribed lipid-lowering agents is statins. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. By blocking this enzyme, statins effectively lower cholesterol levels in the bloodstream.
Another class of lipid-lowering agents is fibric acid derivatives, which primarily target triglyceride levels. These agents activate a nuclear receptor known as PPAR-alpha, which regulates lipid metabolism. By activating PPAR-alpha, fibric acid derivatives enhance the breakdown of triglycerides and increase the elimination of fatty acids from the bloodstream.
Additionally, bile acid sequestrants are often used as lipid-lowering agents. These agents bind to bile acids in the intestine, preventing their reabsorption. As a result, the liver utilizes more cholesterol to produce new bile acids, leading to a decrease in circulating cholesterol levels.
Lipid-lowering agents are available in various formulations, including tablets, capsules, and suspensions, allowing for convenient administration. They are usually prescribed alongside lifestyle modifications, such as dietary changes and regular exercise, to optimize the management of hyperlipidemia.
It is important to note that the use of lipid-lowering agents should be under the supervision of a healthcare professional, as they may have potential side effects and interactions with other medications. Proper monitoring of lipid levels and regular follow-up visits are essential for ensuring the effectiveness and safety of these pharmaceutical agents.
Simvastatin manufacturers | traders | suppliers
We have 25 companies offering Simvastatin produced in 7 different countries.
Get in contact with the supplier of your choice:
- AMARI TRADE ALLIANEC LLP from India, product country of origin IndiaChina
- Rochem International, Inc. from United States, product country of origin United States
- Shandong Octagon Chemicals Limited from China, product country of origin China
- LGM Pharma from United States, product country of origin World
- Zhejiang Jingxin Pharma from China, product country of origin China
- Kolon Life Science from South Korea, product country of origin South Korea
- Osaka Synthetic Chemical Lab from Japan, product country of origin Japan
- Krebs Biochem from India, product country of origin India
- Aquatic Remedies Pvt Ltd from India, product country of origin India
- Sterling Biotech from India, product country of origin India
- Zhejiang Jiangbei from China, product country of origin China
- Southwest Synthetic Pharmaceutical Corp. from China, product country of origin China
- KRKA from Slovenia, product country of origin Unknown
- Shangyu Jingxin from China, product country of origin China
- Themis Medicare from India, product country of origin India
- Zhejiang Hisun Pharma from China, product country of origin China
- UK Chemipharm from South Korea, product country of origin South Korea
- Teva API from Israel, product country of origin Unknown
- Biocon from India, product country of origin India
- Sun Pharma from India, product country of origin India
- Divis Labs. from India, product country of origin India
- Shaoxing Hantai Pharma from China, product country of origin China
- Mylan from India, product country of origin India
- Hetero Labs from India, product country of origin Unknown
- Lupin from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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