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Pegfilgrastim | compare suppliers & send inquiries for free

Here you will find a list of producers, manufacturers and traders of Pegfilgrastim. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

Type: Producer
Origin: India
Gedeon Richter

Type: Producer
Origin: Hungary
Intas Pharma

Type: Producer
Origin: United Kingdom
United Kingdom

Looking for Pegfilgrastim 208265-92-3?

API | Excipient name:
G-CSF, Lenograstim, Pluripoietin  
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About Pegfilgrastim

What can you use it for? Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. It is used to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Some patients with greater risk factors may develop febrile neutropenia from myelosuppressive therapy and are susceptible to an increased risk of developing infections. Although the risk of developing febrile neutropenia is less than 20% in many readily used chemotherapy regimens infections pose risks of hospitalization and mortalities.

Due to the relatively short circulating half-life of filgrastim, a 20 kDa PEG moiety was covalently conjugated to the N-terminus of filgrastim (at the methionine residue) to develop a longer acting version of the drug Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires less frequent dosing than filgrastim. However, pegfilgrastim retains the same biological activity as filgrastim and binds to the same G-CSF receptor to stimulate the proliferation, differentiation, and activation of neutrophils. First developed by Amgen, pegfilgrastim was initially approved by the FDA in 2002 and marketed as Neulasta®. It is typically administered via a subcutaneous injection. There are several pegfilgrastim biosimilars (Fulphila®, Pelgraz® or Lapelga®, Pelmeg®, Udenyca®, Ziextenzo®, and Grasustek®) that are approved for the same therapeutic indication by Health Canada, European Union (EU), and FDA.

Ask the supplier for a certificate of analysis to find out more about the quality of Pegfilgrastim.

Pegfilgrastim manufacturers | traders | suppliers
We have 3 companies offering Pegfilgrastim from 2 different countries.

Get in contact with the supplier of your choice:

  • Biocon from India
  • Gedeon Richter from Hungary
  • Intas Pharma from United Kingdom

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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