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Mk-803 (Lovastatin) API Manufacturers
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Produced in:
Established in: 2011
MOQ: 1 kg
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Producer
Produced in:
Established in: 2021
MOQ: -
Employees: 19
API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides
Small quantity APIs to commercial scale
GMP and USFDA certification based on quantity, order, assignment.
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Producer
Produced in:
Established in: 1995
MOQ: -
Employees: 10000
Fermentation technology Experts
Partnerships with 1200 pharma companies in 100+ countries
US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations
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Producer
Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Looking for Lovastatin API 75330-75-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Lovastatin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Lovastatin
- Synonyms:
- methylcompactin , LOVASTATIN , Lovastatina , Lovastatine , Lovastatinum , Mevacor , Mevinolin , MK-803 , ML-530b
- Cas Number:
- 75330-75-5
- DrugBank number:
- DB00227
- Unique Ingredient Identifier:
- 9LHU78OQFD
About Lovastatin
You can find a short description about Lovastatin here. Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase which catalyzes the conversion of HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as bad cholesterol), and very low-density lipoprotein (VLDL).
Prescribing of statin medications is considered standard practice following any cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes.
You can find more info about this product by clicking on the DB ID above.
Lovastatin is a type of Statins
Statins are a widely prescribed class of pharmaceutical active ingredients (APIs) used for the treatment of high cholesterol and prevention of cardiovascular diseases. These medications work by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver.
Statins are categorized as lipid-lowering agents and are highly effective in reducing levels of low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol. By decreasing LDL cholesterol, statins help to prevent the formation of plaque in the arteries, reducing the risk of heart attacks and strokes.
There are several popular statins available on the market, including atorvastatin, simvastatin, rosuvastatin, and pravastatin. Each statin differs in terms of potency, dosing, and potential drug interactions, allowing healthcare professionals to select the most appropriate option for individual patients.
Statins are typically taken orally in the form of tablets or capsules and are available in different strengths. The dosage is determined by various factors such as the patient's cholesterol levels, cardiovascular risk, and response to treatment.
While statins are generally well-tolerated, they can have side effects such as muscle pain, liver dysfunction, and gastrointestinal disturbances. However, these side effects are relatively rare and are outweighed by the significant cardiovascular benefits of statin therapy.
In conclusion, statins are a vital subclass of pharmaceutical APIs used for managing high cholesterol and reducing the risk of cardiovascular diseases. They effectively lower LDL cholesterol levels and are an essential component of treatment plans for individuals with hyperlipidemia or a high risk of heart disease.
Lovastatin (Statins), classified under Lipid-lowering agents
Lipid-lowering agents are a category of pharmaceutical active ingredients (APIs) that are widely used in the treatment of hyperlipidemia, a condition characterized by elevated levels of lipids (such as cholesterol and triglycerides) in the blood. These agents play a crucial role in managing lipid abnormalities and reducing the risk of cardiovascular diseases.
One of the most commonly prescribed lipid-lowering agents is statins. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. By blocking this enzyme, statins effectively lower cholesterol levels in the bloodstream.
Another class of lipid-lowering agents is fibric acid derivatives, which primarily target triglyceride levels. These agents activate a nuclear receptor known as PPAR-alpha, which regulates lipid metabolism. By activating PPAR-alpha, fibric acid derivatives enhance the breakdown of triglycerides and increase the elimination of fatty acids from the bloodstream.
Additionally, bile acid sequestrants are often used as lipid-lowering agents. These agents bind to bile acids in the intestine, preventing their reabsorption. As a result, the liver utilizes more cholesterol to produce new bile acids, leading to a decrease in circulating cholesterol levels.
Lipid-lowering agents are available in various formulations, including tablets, capsules, and suspensions, allowing for convenient administration. They are usually prescribed alongside lifestyle modifications, such as dietary changes and regular exercise, to optimize the management of hyperlipidemia.
It is important to note that the use of lipid-lowering agents should be under the supervision of a healthcare professional, as they may have potential side effects and interactions with other medications. Proper monitoring of lipid levels and regular follow-up visits are essential for ensuring the effectiveness and safety of these pharmaceutical agents.
Lovastatin manufacturers | traders | suppliers
We have 12 companies offering Lovastatin produced in 3 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China, product country of origin China
- SETV Global from India, product country of origin India
- Biocon from India, product country of origin India
- Aquatic Remedies Pvt Ltd from India, product country of origin India
- Zhejiang Hisun Pharma from China, product country of origin China
- Teva API from Israel, product country of origin Unknown
- Yantai Justaware from China, product country of origin China
- Sterling Biotech from India, product country of origin India
- Fuan Pharma Group (Yantai Justaware) from China, product country of origin China
- Krebs Biochem from India, product country of origin India
- Lupin from India, product country of origin India
- Shaoxing Hantai Pharma from China, product country of origin China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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