Valsartan
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Established in: 1923
MOQ: 25 kg
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Looking for Valsartan 137862-53-4?
- API | Excipient name:
- Valsartan
- Synonyms:
- Diovan , Valsartan Process II
- Cas Number:
- 137862-53-4
- DrugBank number:
- DB00177
- Unique Ingredient Identifier:
- 80M03YXJ7I
About Valsartan
Want to know more about Valsartan? Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, valsartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium. Valsartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions.
Pharmacological blockade of RAAS via AT1 receptor blockade inhibits negative regulatory feedback within RAAS, which is a contributing factor to the pathogenesis and progression of cardiovascular disease, heart failure, and renal disease. In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.
Check who is selling Valsartan in the overview above.
Valsartan manufacturers | traders | suppliers
We have 37 companies offering Valsartan from 7 different countries.
Get in contact with the supplier of your choice:
- SUANFARMA from Spain
- Otto Brandes GmbH from Germany
- Shandong Octagon Chemicals Limited from China
- TIEFENBACHER API + Ingredients from Germany
- Cadila Healthcare from India
- Lupin from India
- Cadila Pharma from India
- Sumitomo Chemical from Japan
- Harman Finochem from India
- Divis Labs. from India
- Kyowa Pharma Chem. from Japan
- Kolon Life Science from South Korea
- Zhejiang Tianyu from China
- Zhejiang Hisun Pharma from China
- Zhejiang Huahai Pharma from China
- Jubilant Generics from India
- Macleods Pharma from India
- Laurus Labs from India
- KRKA from Slovenia
- Menovo from China
- Shin Poong Pharm from South Korea
- Zhuhai Rundu from China
- Signa from Mexico
- Zhejiang Changming from China
- Chromo Labs. from India
- Hetero Labs from India
- Sun Pharma from India
- Ipca Labs. from India
- Mylan from India
- Alembic Pharma from India
- Aurobindo from India
- Daewoong Bio from South Korea
- Dr. Reddy's from India
- Shaoxing Hantai Pharma from China
- Granules India from India
- MSN Life Sciences from India
- Teva Pharma ind. from Israel
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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