Triethylenetetramine
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More than 12 GMP manufacturing facilities (EU, US, India)
Portfolio of more than 240 commercial APIs
We are experts in the cGMP production of highly potent compounds
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14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Looking for Triethylenetetramine 112-24-3?
- Description:
- Here you will find a list of producers, manufacturers and traders of Triethylenetetramine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Triethylenetetramine
- Synonyms:
- Trien , TETA , Trientine
- Cas Number:
- 112-24-3
- DrugBank number:
- DB06824
- Unique Ingredient Identifier:
- SJ76Y07H5F
About Triethylenetetramine
What makes Triethylenetetramine unique? Triethylenetatramine (TETA) is a highly selective divalent Cu(II) chelator and orphan drug that revereses copper overload in tissues. Its salt form, trientine (triethylenetetramine dihydrochloride or 2,2,2-tetramine) was introduced in 1969 as an alternative to D-penicillamine. It consists of a polyamine-like structure different from D-penicillamine, as it lack sulfhydryl groups. It was previously approved by FDA in 1985 as second-line pharmacotherapy for Wilson's disease.
Although penicillamine treatment is believed to be more extensive, TETA therapy has been shown to be an effective initial therapy, even with patients with decompensated liver disease at the outset, and prolonged TETA treatment is not associated with adverse effects as expected in penicillamine treatment. Its clinical applications on cancer, diabetes mellitus, Alzheimer's disease and vascular demetia are being studied.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.
Triethylenetetramine manufacturers | traders | suppliers
We have 7 companies offering Triethylenetetramine from 4 different countries.
Get in contact with the supplier of your choice:
- Curia from United States
- Sumitomo Chemical from Japan
- Teva API from Israel
- NAVINTA from United States
- MSN Organics from India
- Biophore India from India
- Emcure Pharma from India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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