Triethylenetetramine | compare suppliers & send inquiries for free
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What makes Triethylenetetramine unique? Triethylenetatramine (TETA) is a highly selective divalent Cu(II) chelator and orphan drug that revereses copper overload in tissues. Its salt form, trientine (triethylenetetramine dihydrochloride or 2,2,2-tetramine) was introduced in 1969 as an alternative to D-penicillamine. It consists of a polyamine-like structure different from D-penicillamine, as it lack sulfhydryl groups. It was previously approved by FDA in 1985 as second-line pharmacotherapy for Wilson's disease.
Although penicillamine treatment is believed to be more extensive, TETA therapy has been shown to be an effective initial therapy, even with patients with decompensated liver disease at the outset, and prolonged TETA treatment is not associated with adverse effects as expected in penicillamine treatment. Its clinical applications on cancer, diabetes mellitus, Alzheimer's disease and vascular demetia are being studied.
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Triethylenetetramine manufacturers | traders | suppliers
We have 7 companies offering Triethylenetetramine from 3 different countries.
Get in contact with the supplier of your choice:
- ChemWerth from United States
- Emcure Pharma from India
- Teva API from Israel
- Apicore from United States
- MSN Organics from India
- Sumitomo Chemical from Japan
- NAVINTA from United States
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